Searchable abstracts of presentations at key conferences in endocrinology

ea0056p175 | Bone ' Osteoporosis | ECE2018

Acromegaly patients with vertebral fractures, have lower trabecular bone score despite no difference in bone mineral density, than non-fractured patients and healthy controls

Kuzma Martin , Vanuga Peter , Sagova Ivana , Pavai Dusan , Jackuliak Peter , Killinger Zdenko , Binkley Neil , Genant Harry , Payer Juraj

Introduction: Patients with acromegaly, despite normal or even high bone mineral density (BMD), have prevalent vertebral fractures (VFs). HR-pQCT studies in acromegaly have proposed that impaired trabecular bone microarchitecture possibly plays a role in fragility fracture development. As such, we hypothesized that trabecular bone score (TBS) would be low in patients with acromegaly.Aim of the study: To compare BMD and TBS in acromegaly patients with and...

ea0063p93 | Calcium and Bone 1 | ECE2019

Analysis of non-invasive DXA-derived bone structure parameters in patients with acromegaly with regards to vitamin D levels

Kužma Martin , Vaňuga Peter , Sagova Ivana , Pavai Dušan , Jackuliak Peter , Killinger Zdenko , Binkley Neil , Winzenrieth Renaud , Genant Harry , Payer Juraj

Introduction: Patients suffering from acromegaly, despite normal or even higher bone mineral density (BMD), have prevalent vertebral fractures (VFs). Impaired bone microarchitecture is involved fragility fracture development, but vitamin D status could be involved in this impairment.Aim of the study: Comparison of bone parameters such as BMD, trabecular bone score (TBS) and 3D-SHAPER parameters in acromegaly patients according to level of 25(OH)D3.<p...

ea0081p332 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

COVID-19 pneumonia patients with 25(OH)D levels lower than 12 ng/ml are at increased risk of death

Smaha Juraj , Kužma Martin , Brazdilova Kristina , Nachtmann Samuel , Jankovsky Martin , Pastirova Katarina , Gažova Andrea , Jackuliak Peter , Killinger Zdenko , Kyseloviž Jan , Koller Tomaš , Binkley Neil , Payer Juraj

Objectives: There is no consensus about specific serum 25(OH)D levels associated with higher risk of severe outcome in COVID-19 patients. According to the literature patients with serum 25(OH)D levels < 12 ng/ml are clearly deficient at all ages. Our aim was to assess COVID-19 mortality in the settings of severe 25(OH)D deficiency.Methods: A cohort study of 357 COVID-19 patients was conducted. Subjects were monitored until discharge or in-hospital de...