ea0094oc5.5 | Adrenal and Cardiovascular | SFEBES2023
Birch Lara
, Fullerton Josie
, MacKenzie Scott
, Work Lorraine
, Davies Eleanor
Hypertension is the most important risk factor in the development of cerebrovascular diseases including vascular cognitive impairment (VCI). Aldosterone is a key regulator of blood pressure, acting via the mineralocorticoid receptor (MR) in the kidney to promote sodium/water reabsorption. Elevated aldosterone, as in primary aldosteronism (PA) is a risk factor for cerebrovascular disease. In addition to its traditional role, the MR is expressed throughout the brain and vasculat...