Searchable abstracts of presentations at key conferences in endocrinology

ea0062wh8 | Workshop H: Miscellaneous endocrine and metabolic disorders | EU2019

More than just a co-incidence? Hyponatremia as the first manifestation of profound Hypothyroidism

Al-Sharefi Ahmed , Bishop David , Joshi Ashwin

Background: Hyponatraemia is a frequent finding in medical inpatients, where a comprehensive evaluation is warranted to establish the underlying mechanism and guide further management. Whilst the role of confounding medications, syndrome of inappropriate anti-diuretic hormone (SIADH), adrenal insufficiency and polydipsia is well-established as causative factors in the development of hyponatremia, the link between hypothyroidism and hyponatremia is controversial in the medical ...

ea0036P16 | (1) | BSPED2014

Leptin is associated with bone microstructural changes in obese children

Dimitri Paul , Paggiosi Margaret , King David , Bishop Nick , Eastell Richard

Background: Bone mass is low and fracture risk is higher in obese children. We wished to ascertain the relationships of obesity-related changes in hormones with skeletal microstructure.Method: Children aged 8–15 years matched by gender and pubertal stage were recruited into lean and obese groups (18 pairs). We used high resolution peripheral quantitative computed tomography (HRpQCT – resolution-82 μm) to assess three-dimensional cortical a...

ea0034p407 | Thyroid | SFEBES2014

A mediastinal mass in a patient with thyrotoxicosis-recognising the association between thymic hyperplasia and Graves’ disease

Bishop David , Lal Vikram , Fletcher Joanne , Elsaify Wael , Nag Satyajit

Introduction: There is a rare but well documented association between thymic hyperplasia and Graves’ disease particularly in young patients. It is important to recognise this as patients presenting with an anterior mediastinal mass will often undergo extensive investigations to exclude an underlying lymphoproliferative disorder.Case study: A 19-year-old female with symptomatic Graves’ thyrotoxicosis (TSH <0.01 mU/l; FT4 46.8 pmol...