Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep936 | Thyroid | ECE2020

Primary percutaneous coronary intervention induced thyroid storm and acute coronary syndrome: A case report

Bjekic Macut Jelica , Zdravkovic Marija , Vukasin Tamara , Ivanovic Nebojsa , Crevar-Marinovic Slobodanka , Sasa Hinic

Background: Thyroid storm is an extreme disorder that occurs in case of severe thyrotoxicosis. This is a life-threatening condition with mortality rates up to 10–20%. A typical dose of iodinated contrast media (ICM) contains approximately 13.500 µg of free iodide and 15 to 60 g of bound iodine, which represents an acute iodide load of 90 to several hundred thousand times the recommended daily intake of 150 µg. As a result of sudden exposure to high iodide loads...

ea0049gp140 | Female Reproduction | ECE2017

Nonalcoholic fatty liver disease liver fat score (NAFLD-LFS) could be used for the assessment of NAFLD in women with PCOS

Bjekic-Macut Jelica , Bozic-Antic Ivana , Tziomalos Konstantinos , Ilic Dusan , Vojnovic-Milutinovic Danijela , Stanojlovic Olivera , Macut Djuro

Introduction: A relation between polycystic ovary syndrome (PCOS) and nonalcoholic fatty liver disease (NAFLD) was demonstrated recently. Both NAFLD and PCOS are associated with increased risk for type 2 diabetes and cardiovascular disease. NAFLD liver fat score (NAFLD-LFS) has been implicated as a non-invasive surrogate marker for NAFLD. The aim of this study was to identify the prevalence of NAFLD in different PCOS phenotypes using NAFLD-LFS.Methods: W...

ea0044p213 | Reproduction | SFEBES2016

The relation of liver enzymes and insulin resistance in women with polycystic ovary syndrome (PCOS)

Macut Djuro , Bozic-Antic Ivana , Tziomalos Konstantinos , Bjekic-Macut Jelica , Ilic Dusan , Vojnovic-Milutinovic Danijela , Stanojlovic Olivera , Panidis Dimitrios

Introduction: There is a link between polycystic ovary syndrome (PCOS) and nonalcoholic fatty liver disease (NAFLD). Here, we analyzed transaminazes and their relation to insulin resistance (IR) in PCOS women.Methods: We analyzed 600 women with PCOS diagnosed using ESHRE/ASRM criteria (age:25.6±5.9 years, BMI: 30.6±6.9 kg/m2), and 125 BMI-matched healthy controls (age: 31.4±5.3 years, BMI: 29.6±6.8 kg/m2). IR was...

ea0037gp.06.03 | Reproduction: Female and PCOS | ECE2015

Characteristics of lipid profile in different phenotypes of polycystic ovary syndrome

Bjekic-Macut Jelica , Antic Ivana Bozic , Milutinovic Danijela Vojnovic , Ilic Dusan , Kastratovic-Kotlica Biljana , Stanojlovic Olivera , Andric Zoran , Macut Djuro

Introduction: Dyslipidaemia is a common metabolic derangement in polycystic ovary syndrome (PCOS) and may be represented with different lipid alterations. The aim of this study was to evaluate lipid profile in different PCOS phenotypes.Methods: We evaluated 365 PCOS women (PCOS: 25.05±6.24 kg/m2; 25.48±5.21 years) diagnosed using ESHRE/ASRM criteria and 125 BMI-matched healthy women (controls: 25.41±5.16 kg/m2; 30.35&...

ea0035p625 | Female reproduction | ECE2014

Prevalence of dysglycaemia in obese women with polycystic ovary syndrome

Bjekic-Macut Jelica , Antic Ivana Bozic , Milutinovic Danijela Vojnovic , Stanojlovic Olivera , Kastratovic-Kotlica Biljana , Petakov Milan , Ilic Dusan , Macut Djuro

Introduction: Insulin resistance and obesity are common features of polycystic ovary syndrome (PCOS) and both are independently associated with dysglycaemia. The aim of this study was to determine prevalence of dysglycaemia in obese women with PCOS.Methods: PCOS was diagnosed using ESHRE/ASRM criteria. Obesity was defined as BMI ≥25 kg/m2. We evaluated 100 obese women with PCOS (PCOS group: 28.99±3.05 kg/m2; 27.70±5....

ea0056p949 | Female Reproduction | ECE2018

Association of hormonal and metabolic status with carotid intima-media thickness in women with polycystic ovary syndrome

Bjekic-Macut Jelica , Bozic-Antic Ivana , Erceg Snjezana , Civcic Milorad , Ilic Dusan , Vojnovic-Milutinovic Danijela , Stanojlovic Olivera , Macut Djuro

Introduction: Women with polycystic ovary syndrome (PCOS) have numerous risk factors that lead to higher risk for cardiovascular diseases (CVD) and stroke. Measurement of carotid intima-media thickness (CIMT) is a marker of CVD.Methods: We analyzed 399 women with PCOS diagnosed using ESHRE/ASRM criteria (age: 25.5±5.1 years, BMI: 24.9±6.2 kg/m2), and 82 BMI-matched healthy controls (age 29.2±5.9 years, BMI 25.3±8.6 kg/m<sup...

ea0081ep889 | Reproductive and Developmental Endocrinology | ECE2022

Association of SPISE and HOMA-IR indexes with metabolic characteristics of different age groups of women with polycystic ovary syndrome

Opalic Milica , Ognjanovic Sanja , Popovic Bojana , Ilic Dusan , Bjekic - Macut Jelica , Elezovic Valentina , Radic Lena , Milutinovic Danijela Vojnovic , Stanojlovic Olivera , Macut Djuro P.

Introduction: Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy among women during reproductive age. PCOS cardinal manifestations include hyperandrogenism, oligo/anovulation, and/or polycystic ovarian morphology, and is closely linked to metabolic disorders such as obesity and insulin resistance (IR). It was observed that single-point insulin sensitivity estimator (SPISE) index is associated with metabolic abnormalities and could predict glucose regulation ...

ea0063p297 | Reproductive Endocrinology 1 | ECE2019

The natural course of normal weight women with polycystic ovary syndrome: an insight into metabolic changes of a large Caucasian cohort

Livadas Sarantis , Macut Djuro , Bothou Christina , Kuliczkowska-Płaksej Justyna , Vryonidou Andromahi , Bjekic-Macut Jelica , Mouslech Zadalla , Milewicz Andrzej , Panidis Dimitrios

Objective: Polycystic ovary syndrome (PCOS) is hypothesized to originate in foetal life, while its long-term consequences extend beyond menopause. However, the natural course of the disorder has not as yet been elucidated, and recent data suggest differences in the evolution of PCOS according to a woman’s weight. We aimed to define the evolution of normal-weight Caucasian women with PCOS through the years.Design: Cross-sectional case control study</...

ea0049gp139 | Female Reproduction | ECE2017

Sensitivity of hypothalamo-pituitary-adrenal axis in women with PCOS

Macut Djuro , Bozic-Antic Ivana , Bjekic-Macut Jelica , Ilic Dusan , Vojnovic-Milutinovic Danijela , Stanojlovic Olivera , Bogavac Tamara , Popovic Bojana , Isailovic Tatjana , Elezovic Valentina , Ognjanovic Sanja

Introduction: Increased adrenal androgen production is present in 20–60% of women with polycistic ovary syndrome (PCOS). Possible mechanism is not clarified yet and could be related to altered hypothalamic-pituitary-adrenal-axis (HPA) activity or a consequence of adrencortical steroidogenic abnormalities. The aim of the study was to assess HPA sensitivity in PCOS women using different doses of dexamethasone.Methods: We analyzed 359 women with PCOS d...

ea0049ep1114 | Female Reproduction | ECE2017

Novel insulin resistance index using C-peptide is reliable predictor of insulin resistance in women with PCOS

Bozic-Antic Ivana , Ilic Dusan , Bjekic-Macut Jelica , Vojnovic-Milutinovic Danijela , Ognjanovic Sanja , Bogavac Tamara , Popovic Bojana , Isailovic Tatjana , Elezovic Valentina , Stanojlovic Olivera , Macut Djuro

Introduction: Recently, it was suggested that insulin resistance index using C-peptide (CIR) could be a better marker of insulin resistance than homeostasis model assessment (HOMA-IR) in patients with type 2 diabetes mellitus. The aim of this study was to investigate performance of CIR index in PCOS subjects.Methods: We evaluated 187 PCOS women (PCOS: 25.38±6.32 kg/m2; 26.01±5.16 years) diagnosed using ESHRE/ASRM criteria and 42 heal...