ea0041oc13.2 | Pituitary Clinical | ECE2016
Dal Jakob
, Lundby Hoyer Katrine
, Pedersen Steen B
, Magnusson Nils
, Bjerrring Peter
, Frystyk Jan
, Moller Niels
, Jessen Niels
, Jorgensen Jens Otto L
Background: Somatostatin analogue treatment (SA) is used in acromegaly to suppress GH secretion and tumour growth. In addition, SA also suppresses insulin secretion and may impact on GH signalling in peripheral tissues.Objective: To compare GH and insulin signalling in skeletal muscle and adipose tissue in vivo before and after a single exogenous GH bolus in patients with acromegaly controlled by either surgery alone or by ongoing treatment with a slow-r...