Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep827 | Thyroid (non-cancer) | ECE2017

Orbital disease primer for Endocrinologists-not always thyroid associated orbitopathy (TAO): a case vignette

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas

Background: TAO is a rare disease, seriously involving 5% of patients with autoimmune thyroid disease. The clinical presentation may be difficult to distinguish from other orbital conditions.Case 1: A 63-year-old woman was admitted to the Neurology Service for worsening diplopia over the previous six months, with a working diagnosis of myasthenia gravis or multiple sclerosis. The Endocrine Service was consulted because of a long history of Hashimoto&#146...

ea0022p779 | Thyroid | ECE2010

Selenium serum levels in patients with mild Graves' orbitopathy: results of a controlled study

Krassas Gerasimos , Karras Spiros , Boboridis Kostas , Spanos Evagelos

It has been reported recently that selenium (SE) administration over a 6-month period significantly improved the eye involvement in patients with mild GO.Aim: To investigate SE levels in such patients and find out if they differ from controls, finding which might explain the beneficial effect of SE in such patients.Patients: One hundred and four patients (82F) mean age 47.88±827 (S.D.) (range 32–65) with mi...

ea0063p357 | Thyroid 1 | ECE2019

Association between vitamin D receptor gene polymorphisms and Graves’ disease: a systematic review and meta-analysis

Anagnostis Panagiotis , Veneti Stavroula , Adamidou Fotini , Artzouchaltzi Aikterini-Maria , Boboridis Kostas , Kita Marina

Introduction: The pathogenesis of Graves’ disease (GD) and Graves’ orbitopathy (GO) is not completely understood. On the other hand, vitamin D receptor (VDR) gene polymorphisms have been associated with susceptibility to a variety of chronic autoimmune diseases. The primary aim of this study was to synthesize the best available evidence regarding the association between VDR gene polymorphisms and risk of GD. Secondary aim was to search for their association with GO.<...

ea0049ep828 | Thyroid (non-cancer) | ECE2017

Management of very severe Graves’ orbitopathy with low dose rituximab: report of two cases

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas , Kita Marina

Introduction: Although Graves’ orbitopathy (GO) is common in the course of Graves’ disease, dysthyroid optic neuropathy and corneal breakdown are rare. We describe two cases of severe GO treated successfully with rituximab.Case 1: A 50-year-old female smoker with Graves’disease, presented with disfiguring eyelid edema, exophthalmos and diplopia, preserved visual acuity and clinical activity score (CAS) ≥ 5. She received pulsed medrox...

ea0035p314 | Clinical case reports Thyroid/Others | ECE2014

Refractory Graves' ophthalmopathy treated with rituximab

Adamidou Fotini , Poulasouhidou Maria , Boboridis Kostas , Hambidis Vassilis , Anagnostis Panagiotis , Kita Marina

Introduction: Graves’ ophthalmopathy (GO) is common in the course of Graves’ disease, but optic neuropathy is present in only ~5% of patients with GO. We present a case of recalcitrant Graves’ orbitopathy with late development of neuropathy, satisfactorily treated with rituximab.Case report: A 50-year-old female smoker was referred to our department for further management of Graves’ disease with associated GO. She complained of worsen...