Endocrine Abstracts

Introduction: Polymorphisms of genes involved in the growth process are an important cause of growth hormone deficiency (isolated form). Isolated growth hormone deficiency can be caused by genetic defects in about 10% of patients, in 34% of cases it is a consequence of familial pathology, and 4% are sporadic cases. The nuclear receptor for vitamin D mediates most of the biological functions of this vitamin. It belongs to the steroid hormone receptor family, the gene for which ...