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ea0066oc6.3 | Oral Communications 6 | BSPED2019

Here’s the POInT: a multicentre European Primary Oral Insulin Trial

Bendor-Samuel Owen , Wishlade Tabitha , Vatish Manu , Ziegler Anette-Gabriele , Bonifacio Ezio , Todd John A , Snape Matthew , Group GPPAD Study

Introduction: The successful prevention of type 1 diabetes (T1D) is a major clinical goal. The pathogenesis is multifactorial, with genetic and environmental influences that lead to a break in immune tolerance toward pancreatic beta cells. Through a number of prospective cohort studies, it is now understood that the presence of two or more diabetes-associated autoantibodies is highly predictive of future T1D diagnosis. In addition to the genetic rationale (insulin gene sequenc...

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ea0103p91 | Diabetes 5 | BSPED2024

Strategizing early detection and follow-up for type 1 diabetes: The EDENT1FI project

Besser Rachel , Vercauteren Jurgen , Overbergh Lut , Bonifacio Ezio , Narendran Parth , Bergholdt Regine , Strube Thorsten , Dayan Colin , Niemoeller Elisabeth , Bosi Emanuele , Pociot Flemming , Latres Esther , Hurtado Carmen , Raposo Joao Filipe. , Baccara-Dinet Marie , Reschke Felix , Fogh Kamille , Cohen Ohad , Peakman Mark , Ziegler Anette , Mathieu Chantal

Background and aims: European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception (EDENT1FI) targets early Type 1 Diabetes (T1D) detection to reduce the risk of diabetic ketoacidosis, delay disease progression, improve long-term health outcomes and provide a softer landing to insulin therapy. It aims to refine screening and support in early-diagnosed individuals to allow implementation in the clinical care setting.<p class="a...

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Endocrine Abstracts

Here’s the POInT: a multicentre European Primary Oral Insulin Trial

Strategizing early detection and follow-up for type 1 diabetes: The EDENT1FI project

BiosciAbstracts