Searchable abstracts of presentations at key conferences in endocrinology

ea0073d3.1 | Debate 3: Selenium for autoimmune thyroid disorders: necessary or unnecessary? | ECE2021

AGAINST: Selenium for autoimmune thyroid disorders: necessary or unnecessary?

Bonnema Steen J.

Selenium is an essential element for humans. Important dietary sources of selenium include meat, seafood, and grains. Selenium is incorporated into a range of selenoenzymes with antioxidant properties. Being crucial for the activity of the deiodinase enzymes, selenium is especially important for the synthesis and metabolism of thyroid hormones. Selenium in relation to thyroid diseases has been widely explored. Epidemiological studies have shown that a low selenium status is as...

ea0070ep516 | Thyroid | ECE2020

Treatment of hypothyroidism does not affect whole-body oxidative stress, as measured by biomarkers of RNA and DNA damage

Ryom Riis Kamilla , Larsen Camilla , Winther Kristian H. , Larsen Emil L. , Ellervik Christina , Hegedüs Laszlo , Brix Thomas , Poulsen Henrik E. , Bonnema Steen J.

Background: Hyperthyroidism as well as hypothyroidism have been associated with oxidative stress, caused by an imbalance between pro-oxidants and antioxidants. Oxidative stress may damage the genomic apparatus and other cellular structures. Urinary excretion of 8-oxo-7.8-dihydroguanosine (8-oxoGuo) and 8-oxo-7.8-dihydro-2’-deoxyguanosine (8-oxodG), respectively, represent global RNA and DNA oxidation, thus reflecting oxidatively generated modification of nucleic acids in...

ea0073oc5.2 | Oral Communications 5: Thyroid | ECE2021

Use of thyroid hormones in hypothyroid and euthyroid patients: A 2020 THESIS* questionnaire survey of members of the Danish Endocrine Society (*Treatment of hypothyroidism in europe by specialists: An international survey)

Riis Kamilla Ryom , Froelich Jacob , Hegedüs Laszlo , Negro Roberto , Attanasio Roberto , Nagy Endre , Papini Enrico , Perros Petros , Bonnema Steen J.

PurposeThe standard treatment of hypothyroidism is levothyroxine (LT4), which is available as tablets or soft-gel capsules in Denmark. This study aimed to investigate Danish endocrinologistsÂ’ use of thyroid hormones in hypothyroid and euthyroid patients.MethodAn e-mail with an invitation to participate in an online survey investigating practices about substitution with thyroid hormones was sent to all me...