ea0081ep664 | Pituitary and Neuroendocrinology | ECE2022
Ali Rashid Razan
, Boot Christopher S
, James Andy
, Mamoojee Yaasir
Background: Diagnostic work-up for Cushing s syndrome (CS) can be challenging, with variable performance characteristics on screening tests. We were recently referred a young female patient with Cushings disease (CD) due to a microadenoma. She presented with a seizure and initial biochemical work-up included a Synacthen stimulation test (SST). Her peak cortisol rose to over 1,000 nmol/l. Exaggerated response during SST is expected in hyperestrogenic states due to e...