ea0041gp55 | Cardiovascular endocrinology | ECE2016
Pepin JL
, Galerneau LM
, Borel AL
, Chabre O
, Sapene M
, Stach B
, Girey-Rannaud J
, Tamisier R
, Caron Ph
Introduction: Insulin-like growth factor-1 (IGF-I), the main growth factor associated with GH secretion, directly opposes endothelial dysfunction and limit early atherosclerosis by favoring nitric oxide production, promoting insulin sensitivity and preventing postprandial dyslipidemia. A low serum IGF-I level has been reported in patients with OSA syndrome and might be one of the mechanisms underlying cardio-metabolic risks in OSA patients. IGF-1 levels were evaluated in a lar...