Endocrine Abstracts

Background: Hypopituitarism is often part of the presenting clinical manifestation for patients with non-functioning pituitary macroadenomas (NFPMs). Rate of recovery of hypothalamic-pituitary endocrine axes following therapy is uncertain with no clear predictive factors.Aims: The aim of this study was to assess the degree of hypopituitarism recovery following surgery and radiotherapy in patients with NFPMs. Methods: All patients t...

Background: Non-functioning pituitary macroadenomas (NFPMs) may present with hypopituitarism. Pituitary surgery and radiotherapy pose an additional risk to pituitary function.Aims: The aim of this study was to assess the incidence of hypopituitarism pre-operatively and the impact of surgery and radiotherapy on pituitary function. Methods: All patients treated with surgery and radiotherapy for NFPMs between 1987 and 2018 with more t...

Background: The management of craniopharyngiomas remains controversial.Objective: This study sought to examine temporal trends in the management of craniopharyngioma and their impact on long-term patient outcomes, with focus on endocrine consequences.Methods: This was a cross sectional, multicentre study. Patients treated between 1951 and 2015 were identified and divided into four quartiles based on the date of initial surgery. Pat...