Endocrine Abstracts

Background: Autoimmune polyendocrinopathy-candidiasis–ectodermal dystrophy (APECED) is a rare monogenic disorder characterized by various loss-of-function mutations in the AIRE gene. Clinical manifestations in this case included chronic mucocutaneous candidiasis, hypoparathyroidism, primary adrenal insufficiency, type 1 diabetes, and vitiligo. Additionally, the patient had a history of primary hypothyroidism and epilepsy.Clinical Case: Hypopituitari...

We present the case of a patient with a diagnosis of thyroid cancer who has developed multiple, sequential autoimmune conditions. Our patient, a now 41 year-old female, was initially diagnosed with Follicular Thyroid Cancer in the context of pre-existing autoimmune hypothyroidism evidenced by serum Anti-Thyroid Microsomal antibodies as well as lymphocytic thyroiditis on post-operative histopathology. The association between autoimmune thyroid disease and Thyroid Cancer has bee...

Introduction: Patients with Diabetes have a higher risk of lower urinary tract dysfunction/symptoms (LUTS) compared to those without diabetes. Causative factors include autonomic, detrusor, and urothelial dysfunction, microvascular ischaemic changes, and glycosuria. With a shift towards holistic diabetes management, this study examined whether urinary dysfunction is routinely addressed in outpatient settings and whether Diabetes speciality teams feel equipped to manage this is...

Introduction: Unexplained falls are a common rationale for emergency presentations amongst older adults. Admissions are associated with significant morbidity. We present a case series of two older adults presenting following collapse, with resultant diagnosis of insulin-mediated hypoglycaemia.Case 1: 79 year-old woman presenting following a presyncopal event. In the weeks preceding admission, described lethargy and weight loss, with associated palpitatio...