Searchable abstracts of presentations at key conferences in endocrinology

ea0069p8 | Poster Presentations | SFENCC2020

Management of Adipsic Cranial Diabetes Insipidus while evading methotrexate toxicity

Gunda Rohini , Gaur Smriti , Bowles Kristian , Myint Khin Swe , Ahluwalia Rupa

Introduction: We present a challenging case of central diabetes insipidus secondary to hypothalamic large B cell lymphoma. These are rare tumors accounting for less than 1% of lymphomas. Conventional treatment involves the MATRIX regime (methotrexate, rituximab, thiotepa, cytarabine) chemotherapy, coupled with intensive intravenous fluid therapy to avoid methotrexate toxicity. The main challenges in the management of this case were maintaining fluid and electrolyte balance in ...