Searchable abstracts of presentations at key conferences in endocrinology

ea0081p75 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Type 1 diabetes technology and quality of life: glucose control and beyond

Irina Briganti Silvia , Maggi Daria , Strollo Rocky , Kyanvash Shadi , Lanza Oreste , Pozzilli Paolo , Manfrini Silvia

Background: Technological advances in continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) should aim to improve glucose control and quality of life in patients diagnosed type 1 diabetes (T1D).Aim: The aim of our study was to compare different CGM and CSII devices on these targets.Methods: Sixty-nine T1D patients (mean age 39±12; 31 males) were recruited. 36 were on multiple daily insulin inj...

ea0081p321 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Effect of a novel-app based strategy for carbohydrate counting on glucose control in type 1 diabetes

Briganti Silvia Irina , Strollo Rocky , Maggi Daria , Kyanvash Shadi , Lanza Oreste , Manfrini Silvia , Pozzilli Paolo

Background: carbohydrate counting is often performed inaccurately by patients with type 1 diabetes (T1D). We hypothesized that mobile App ‘Dietrometro’, that estimates CHO content of food figures, would ameliorate glucose control.Aim: To study the effect of ‘Dietometro’ on glucose control.Methods: 54 T1D subjects (aged 18-60 years, 26 males), on multiple daily injections (n=23) or continuous subcutaneou...

ea0081ep191 | Calcium and Bone | ECE2022

Primary hyperparathyroidism in the setting of previous roux-en-Y gastric bypass: a case report

Monte Lavinia , Tuccinardi Dario , Strollo Rocky , Briganti Silvia , Rausa Donatella , Pozzilli Paolo , Napoli Nicola , Manfrini Silvia

Introduction: Primary hyperparathyroidism (PHPT) after roux-en-Y gastric bypass (RYGB) is poorly described. The diagnosis can be difficult as secondary hyperparathyroidism(SHPT) commonly occurs in patients after RYGB due to calcium hypoabsorption and vitamin D deficiency.Observation: We present the case of a 50-year-old female with a history of normocalcemic hyperparathyroidism and nephrolithiasis. In 2005 the patient had undergone RYGB. During the first...

ea0081ep1049 | Thyroid | ECE2022

Worsening dysphagia and dysphonia: a case report

Rausa Donatella , Briganti Silvia Irina , Rossini Giovanni , Monte Lavinia , Napoli Nicola , Manfrini Silvia

Premise: multinodular goiter and compressive symptoms in the neck could not be necessarily associated.Case-report: A 82-year-old woman diagnosed follicular lymphoma in 2017 reached to the Emergency Department in Agoust 2021 because of a progressive and worsening dysphagia and dysphonia, begun six weeks before. The patient complained a weight loss of about 8 kg due to the inability in feeding. Her medical history was relevant for thyroid goiter, known sin...

ea0049oc6.2 | Diabetes therapy and complications | ECE2017

Insulin-mimetic effects of short-term Rapamycin in type 1 diabetic patients prior islet transplantation

Ermetici Federica , Briganti Silvia , Benedini Stefano , Codella Roberto , Maffi Paola , Caldara Rossana , Secchi Antonio , Piemonti Lorenzo , Alejandro Rodolfo , Ricordi Camillo , Luzi Livio

It has been suggested that the selective m-TOR inhibitor, Rapamycin, has been improved the success pancreatic islet allotransplantation (ITx) in type 1 diabetic patients (T1DM). Forty-one ITx were studied. Thirteen T1DM in poor glycemic control underwent a 45-days Rapamycin before ITx followed by standard Edmonton Protocol (EP, group 1, Milan), and they were compared to 28 T1DM patients undergoing EP (group 2, Miami). Outcome measures were daily insulin requirement (DIR), HbA1...

ea0035p766 | Obesity | ECE2014

Vertebral bone marrow fat is increased in obese women: relationship with epicardial fat

Ermetici Federica , Briganti Silvia , Delnevo Alessandra , Cannao Paola , Secchi Francesco , Leo Gianni Di , Bandera Francesco , Dozio Elena , Romanelli Massimiliano Marco Corsi , Sardanelli Francesco , Morricone Lelio , Malavazos Alexis Elias

Introduction: Bone marrow fat is considered a risk factor for osteoporosis and fragility fracture. It is not clear if bone marrow adiposity is increased in obesity and how it relates to other compartments of adipose tissue, in particular visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and epicardial adipose tissue (EAT).Aim: To evaluate bone marrow adiposity in obese as compared with normal weight women.Design: Tw...

ea0063gp20 | Calcium and Bone 1 | ECE2019

Clinical, biochemical and radiological profile of normocalcaemic hyperparathyroidism: a multicentric cross-sectional evaluation

Naciu Anda Mihaela , Tabacco Gaia , Falcone Stefania , Santonati Assunta , Maggi Daria , D'Onofrio Luca , Briganti Silvia Irina , Castellitto Domenico , Casini Alessandro , Pedone Claudio , Fabbri Andrea , Napoli Nicola , Pozzilli Paolo , Manfrini Silvia , Cesareo Roberto , Palermo Andrea

Background: The normocalcaemic hyperparathyroidism (NHPT) has been defined as a condition with persistently normal total and ionized calcium levels in the presence of high levels of PTH. The clinical aspects of NHPT have been evaluated in different cohorts but the interpretation of these findings is confounded by differing methods used to rule out secondary hyperparathyroidism and by the small number of NHPT subjects enrolled. Up to now, there is no information available that ...