ea0081p202 | Thyroid | ECE2022
Lopez Alcantara Nuria
, Geiszler Cathleen
, Naujack Alison-Michelle
, Chen Yingfu
, Taege Natalie
, Britsemmer Jan H.
, Vinicius Monteiro De Assis Leonardo
, Oster Henrik
, Spranger Joachim
, Wirth Eva
, Nogueiras Ruben
, Kirchner Henriette
, Mittag Jens
Background and Aim: Hepatic thyroid hormone (TH) signalling plays an important role in onset and progression of liver diseases. Patients with altered thyroid hormone regulation in the liver, leading to a local hypothyroid, are at higher risk of developing non-alcoholic fatty liver disease (NAFLD). Treatment with thyroid hormones proved to be a promising therapy for these patients, slowing the progression of NAFLD to non-alcoholic steatohepatitis (NASH), a more advanced stage o...