Searchable abstracts of presentations at key conferences in endocrinology

ea0012p11 | Clinical case reports/Governance | SFE2006

Sporadic pancreatic somatostatinomas: 3 cases

Brooke AM , Cheung TT , Metcalfe K , Carlsen E , Berney D , Bhattacharya S , Plowman PN , Monson JP , Drake WM

Sporadic somatostatinomas are rare neuroendocrine tumours (NETs), classically presenting with hyperglycaemia, cholelithiasis and steatorrhoea. The mainstay of treatment is surgical resection; other aspects of management remain uncertain. We report 3 cases. Case 1: A 55 year-old female presented with abdominal discomfort and steatorrhoea. Computed tomography (CT) demonstrated a 9 cm pancreatic mass. Biopsy suggested a NET. Somatostatin (SMS) was 160 pmol/l (normal 0-150)...

ea0011p625 | Neuroendocrinology and behaviour | ECE2006

Dehydroepiandrosterone (DHEA) improves psychological well-being in male and female hypopituitary patients in addition to growth hormone replacement (GHR)

Brooke AM , Kalingag LA , Miraki-Moud F , Camacho-Hubner C , Maher KT , Walker DM , Hinson JP , Monson JP

Hypopituitarism is associated with profound androgen deficiency, even in patients who are adrenocorticotrophic hormone (ACTH) replete. DHEA has been shown to have a beneficial effect on well-being in patients with adrenal failure. We hypothesised that DHEA may be additive to the known effects of GH on psychological well-being in patients with hypopituitarism. In a double blind placebo controlled trial 50 mg DHEA or placebo was added to standard replacement, including growth ho...