Searchable abstracts of presentations at key conferences in endocrinology

ea0084ps3-15-135 | Thyroid Cancer Diagnosis & Treatment | ETA2022

Clinical relevance of lower titer thyroglobulin (TG) autoantibodies in patients with differentiated thyroid carcinoma

Dekker Bernadette , van der Horst-Schrivers Anouk , Brouwers A.H. , Shuford Chris , Kema Ido , Muller Kobold Anneke , Links Thera

Objectives: Thyroglobulin (Tg) is an established tumor marker for differentiated thyroid carcinoma (DTC) patients. However, Tg immunoassays can be subject to autoantibody (TgAb) interference resulting in incorrect Tg values. Tg measurement with liquid chromatography-tandem mass spectrometry (LC-MS/MS) could be promising in patients with TgAbs. In this study, we compared a Tg immunoradiometric assay (Tg-IRMA) and a Tg-LC-MS/MS analytically in the presence of TgAbs. Furthermore,...

ea0101ps1-05-03 | Clinical thyroid cancer research-1 | ETA2024

Toxicity and quality of life after locoregional radiotherapy in patients with thyroid cancer

van den End Job , Jager Eline , Verbeek Hans , Oldehinkel Edwin , Jansen Liesbeth , Brouwers A.H. , Zandee Wouter , Kruijff Schelto , Links Thera

Objectives: To analyze acute and late toxicities and long-term quality of life (QoL) in patients who underwent locoregional external beam radiotherapy (EBRT) for thyroid cancer and to assess the correlation of QoL with treatment characteristics.Methods: Patients treated with locoregional EBRT for thyroid cancer at University Medical Centre Groningen (UMCG) (2007-2023) were included. Patient/treatment characteristics were extracted from patient files retr...

ea0049ep155 | Endocrine tumours and neoplasia | ECE2017

False positive findings on 6-[18F]fluor-L-3,4-dihydroxyphenylalanine Positron Emission Tomography (18F-FDOPA-PET) performed for imaging of neuroendocrine tumors

Berends MA , Bolt JW , Kerstens MN , Links TP , Korpershoek E , de Krijger RR , Walenkamp AME , Noordzij W , van Etten B , Kats-Urgurlu G , Brouwers AH , van der Horst-Schrivers ANA

Background/Aim: Neuroendocrine tumors (NETs) are rare tumors arising from neuroendocrine cells throughout the body. Positron Emission Tomography (PET) scanning with 6-[18F]fluor-L-3,4-dihydroxyphenylalanine (18F-FDOPA) has been shown to be a valuable technique for the imaging of NETs. While the sensitivity has been assessed numerously, studies systematically describing false positive results, other than physiological variants, are lacking. Our aim was to systematica...

ea0084op-12-62 | Oral Session 12: Nodules and Diagnostic | ETA2022

Progressive diastolic dysfunction in survivors of pediatric differentiated thyroid carcinoma

Reichert Antoinette , Nies Marloes , tissing wim , Muller Kobold Anneke , Klein Hesselink Marielle , Brouwers A.H. , Havekes Bastiaan , van den heuvel-eibrink marry , van der pal helena , plukker john , Van Santen Hanneke , corssmit eleonora , Teodora Netea-Maier Romana , Peeters Robin , van Dam Eveline , burgerhof johannes , van der Meer Peter , bocca gianni , Links Thera

Background: Pediatric differentiated thyroid cancer (DTC) has an excellent prognosis, but has unknown late effects of treatment. Initial cardiac evaluation showed subclinical diastolic dysfunction in 20% of adult survivors. In this follow-up study, we determined the clinical course of this finding.Methods: This multicenter study, conducted between 2018 and 2020, re-evaluated survivors 5 years after the first evaluation. The primary endpoint was echocardi...