Searchable abstracts of presentations at key conferences in endocrinology

ea0020p467 | Obesity and Metabolism | ECE2009

Plasma monocyte chemoattractant protein-1 and macrophage inflammatory protein-1α are increased in patients with polycystic ovary syndrome and associated with adiposity, but unaffected by pioglitazone treatment

Glintborg Dorte , Andersen Marianne , Richelsen Bjorn , Bruun Jens

Objective: PCOS patients are often characterized by insulin resistance, abdominal obesity, and low-grade inflammation. Insulin sensitizing treatment reduces the inflammatory state, but the effect on serum levels of chemokines such as migration inhibitor factor (MIF), monocyte chemoattractant protein (MCP)-1, and macrophage inflammatory protein (MIP)-1α have not previously been evaluated in PCOS.Research design and methods: Plasma chemokine levels (M...

ea0020p486 | Obesity and Metabolism | ECE2009

The effect of weight loss on serum mannose binding lectin levels

Hoeyem Pernille H , Bruun Jens M , Pedersen Steen B , Richelsen Bjoern , Christiansen Jens S , Hansen Troels K

Background: High levels of mannose-binding lectin (MBL), an activator of complement, have been associated with increased mortality and risk of albuminuria in patients with type 2 diabetes. It is not known if MBL is synthesized in human adipose tissue and the effects of weight loss and changes in insulin sensitivity on MBL levels have been poorly elucidated.Methods: Of 36 nondiabetic obese subjects received a very low-calorie diet (VLCD) of 800 kcal/day f...

ea0032p638 | Male reproduction | ECE2013

Strength training and testosterone treatment have opposing effects on migration inhibitor factor levels in ageing men

Glintborg Dorte , L Christensen Louise , Kvorning Thue , Larsen Rasmus , Brixen Kim , M Hougaard David , Richelsen Bjorn , M Bruun Jens , S Andersen Marianne

Objective: The beneficial effects of testosterone treatment (TT) in men with low normal testosterone levels are debated. Chemokine levels have not previously been evaluated during TT in combination with strength training (ST).Design: A randomized, double-blinded, placebo-controlled study of 6 months TT (gel) in 54 men aged 60–78 years with bioavailable testosterone (BioT) <7.3 nmol/l and waist circumference >94 cm randomized to TT (50–1...