Searchable abstracts of presentations at key conferences in endocrinology

ea0032p886 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Short-term exercise-induced GH response in athletes: differential results for runners and bikers when tested on bicycle

Zueger Thomas , Bucher Julie , Christ Emanuel , Stettler Christoph

Background/introduction: SUB:Pituitary – Clinical (Generously supported by IPSEN)We have previously shown that GH assessment during a standardized aerobic exercise of moderate intensity is a reliable test with high diagnostic accuracy in predicting severe GH deficiency (GHD) in adult individuals. However, these studies comprised comparably long exercise durations around 60 min or longer. To improve clinical applicability of exercise testing in the diagnosis of GH...

ea0041gp53 | Cardiovascular endocrinology | ECE2016

Different repletion of intramyocellular lipid (IMCL) in patients with growth hormone deficiency (GHD) compared to control subjects (CS) 24 h after a 2-h aerobic exercise

Jenni Stefan , Loher Hannah , Bucher Julie , Ith Michael , Boesch Chris , Kreis Roland , Christ Emanuel R

Background: We and others have shown that ectopic lipids are flexible fuel stores in healthy subjects, in patients with type 1 diabetes or with GHD. IMCL are depleted by exercise and repleted by diet, whereas intrahepatocellular lipids (IHCL) are increased immediately after exercise. It is unclear whether the exercise-induced flexibility of IMCL and IHCL persists until 24 h and whether healthy subjects and patients with GHD behave differently.Methods: Ma...

ea0035p200 | Cardiovascular Endocrinology &amp; Lipid Metabolism | ECE2014

Flexibility of ectopic lipids in physically active, healthy individuals

Bucher Julie , Krusi Marion , Kreis Roland , Zuger Thomas , Ith Michael , Stettler Christoph , Boesch Chris

Introduction: Ectopic lipids are fuel stores in non-adipose tissues (i.e. skeletal muscle (IMCL), liver (IHCL), heart (ICCL)). An aerobic-exercise bout leads to a decrease in IMCL (‘working tissues’), whereas it is not established whether a single but of exercise influences IHCL or ICCL.Increased IMCL and IHCL have been related to impaired insulin action in skeletal muscle and liver. It is hypothesized that fat availability (subcutaneous and vi...

ea0032p180 | Cardiovascular Endocrinology &amp; Lipid Metabolism | ECE2013

The effect of aerobic exercise on ectopic lipids intramyocellular, intrahepatocellular, and intracardiomyocellular lipids in physically active, healthy individuals

Kruesi Marion , Bucher Julie , Kreis Roland , Ith Michael , Zueger Thomas , Stettler Christoph , Boesch Chris , Christ Emanuel

Introduction: Ectopic lipids are fuel stores in non-adipose tissues (i.e. skeletal muscle (IMCL), liver (IHCL), and heart (ICCL)). It is recognized that IMCL can be depleted by physical activity and repleted by dietary fat intake indicating metabolic flexibility. In contrast, preliminary data suggested that aerobic exercise increases IHCL. Data on the acute effect of aerobic exercise on ICCL is scarce.Increased IMCL and IHCL have consistently been relate...