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Endocrine Abstracts

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ea0056gp45 | Adrenal medulla and NETs | ECE2018

The 10 Hounsfield Units cut-off value on unenhanced CT imaging is highly sensitive to diagnose pheochromocytoma: a multicenter study

Buitenwerf E , Korteweg T , Haag MSC , Feelders RA , Timmers HJLM , Canu L , Haak HR , Bisschop PHLT , Eekhoff EMW , Corssmit EPM , Dullaart RPF , Links TP , Kerstens MN

Introduction: A substantial proportion of pheochromocytomas (PCC) are detected during the work-up of an adrenal incidentaloma. Recently it has been suggested that in case of an adrenal incidentaloma with an unenhanced attenuation value <10 Hounsfield Units (HU) on CT imaging biochemical testing to rule out PCC is unnecessary. We aimed to determine the sensitivity of the 10 HU cut-off value to detect pheochromocytoma.Methods: Retrospective multicenter...
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ea0056oc7.5 | Genomic and clinical aspects of endocrine tumours | ECE2018

Randomized trial comparing phenoxybenzamine and doxazosine for preoperative treatment of patients with a pheochromocytoma (PRESCRIPT)

Buitenwerf E , Osinga TE , Timmers HJLM , Lenders JWM , Feelders RA , Eekhoff EMW , Haak HR , Corssmit EPM , Bisschop PHLT , Valk GD , GrooteVeldman R , Dullaart RPF , Links TP , Voogd MF , Wietasch JKG , Kerstens MN

Background: Administration of α-adrenergic receptor antagonists is recommended before resection of a pheochromocytoma (PCC) in order to prevent perioperative cardiovascular complications. For this purpose either phenoxybenzamine (PXB) or doxazosin (DOX) is commonly prescribed. We conducted the first randomized controlled trial comparing the efficacy of PXB and DOX in controlling perioperative hemodynamics in patients undergoing PCC resection (ClinicalTrials.gov:NCT0137989...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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