Searchable abstracts of presentations at key conferences in endocrinology

ea0025p45 | Clinical biochemistry | SFEBES2011

Audit on the management of adrenal incidentaloma

Bujawansa Sumudu , Bowen-Jones David

Introduction: Adrenal incidentaloma is defined as a clinically inapparent adrenal mass that is incidentally detected after imaging studies conducted for reasons other than the evaluation of the adrenal glands. Existing guidance suggests that excess catecholamine and cortisol secretion should be ruled out all cases and excess aldosterone secretion should be ruled out hypertensive patients. Certain features on CT scanning such as a Hounsfield value of over 10 are useful in diffe...

ea0021p30 | Clinical practice/governance and case reports | SFEBES2009

Unusual presentation of a phaeochromocytoma

Bujawansa Sumudu , Leong King Sun

Background: Phaeochromocytoma are rare catecholamine secreting tumours and may present with hypertension, orthostatic hypotension, tachycardia and even cardiogenic shock. These tumours can easily be missed particularly in patients presenting with other disorders. We present a case of a patient with severe community acquired pneumonia who despite overwhelming sepsis was severely hypertensive.The case: JP was a 33-year-old man who was previously fit and we...

ea0062p48 | Poster Presentations | EU2019

Partial cranial diabetes insipidus in breast cancer: invisible pituitary metastases or uncanny coincidence

Westall Sam , Sullivan Heather , McNulty Sid , Bujawansa Sumudu , Narayanan Prakash

Case history: PD is a 57-year-old female teacher who presented to her GP in October 2017 with lethargy, dyspnoea and anaemia. Bone marrow biopsy followed by a CT scan of her chest and abdomen confirmed lobular breast cancer with peritoneal and bone metastases (ER+/HER2−). The patient also had an MRI scan of her head to assess for intracranial metastatic disease which was negative at the start of December 2017. She was commenced on letrozole, palbociclib and denosumab. A ...

ea0094p14 | Adrenal and Cardiovascular | SFEBES2023

Evaluation of inpatient hyponatremia: if formal recognition (coding) of hyponatremia makes a difference in management and outcomes

Aung Ei Thuzar , Balafshan Tala , Bujawansa Sumudu , Narayanan Ram Prakash

Introduction: Hyponatremia is a common electrolyte disorder in clinical practice. We did a retrospective analysis of 100 patients admitted between Jan 2019 to June 2019 with moderate hyponatremia (Na-125-129 mmol/l) to see if there was a difference in management and outcome of the patients who were formally coded as hyponatremia and those who were not coded as such.Results: Mean age was 74 years in the coded group (n...

ea0086p39 | Bone and Calcium | SFEBES2022

An unusual case of severe hypercalcaemia due to treatment resistant Graves’ disease

Thuzar Aung Ei , Sheokand Ajasra , Prakash Narayanan Ram , Balafshan Tala , McNulty Sid , Furlong Niall , Bujawansa Sumudu

A 32-years-old lady was admitted with raised calcium. She had palpitation, sweating, 3 stones weight loss and neck swelling. She was diagnosed with Graves’ disease 5 months ago. Her mother had history of thyroid disease but no family history of hypercalcaemia. She had a small goitre and lid lag on examination. On admission, adjusted calcium was 3.04 mmol/l. PTH was < 0.5 pmol/l. Phosphate, vitamin-D, kidney functions, cortisol, myeloma screen and ACE levels ...

ea0086p341 | Metabolism, Obesity and Diabetes | SFEBES2022

New onset diabetes triggered by use of growth hormone secretogogue for body building, a case report

Thuzar Aung Ei , Sheokand Ajasra , Westall Samuel , Balafshan Tala , Prakash Narayanan Ram , Bujawansa Sumudu

Introduction: Growth hormone secretogogues (GHS) are popular among body building communities as muscle bulking agents. We present an interesting case of new onset diabetes induced by a combination of GHS and selective androgen receptor modulators (SARMs).Case report: A 34-years body builder was referred by his GP due to a 3-week history of polyuria, polydipsia and fatigue. He had recently used one cycle of a combination tablet which contained Ibutamoren ...

ea0028p254 | Pituitary | SFEBES2012

The Pituitary Apoplexy Score (PAS) in the evaluation and management of acute pituitary apoplexy: a single centre experience from the United Kingdom

Thondam Sravan , Bujawansa Sumudu , Noonan Carmel , MacFarlane Ian , Javadpour Mohsen , Daousi Christina

Aims: The United Kingdom (UK) guidelines for management of acute pituitary apoplexy recommend the Pituitary Apoplexy Score (PAS) to objectively assess clinical severity of this rare neuro-endocrine emergency. We aimed to apply retrospectively this scoring tool to a large, single centre series of patients with acute pituitary apoplexy, and to determine its applicability in the management of these patients in the acute setting.Methods: Retrospective study ...

ea0025p252 | Pituitary | SFEBES2011

An uncommon cause of panhypopituitarism

Srinivas-Shankar Upendram , Bujawansa Sumudu , Leonard Niamh , Clark Peter , Syndikus Isabel , Forsyth Leigh , Hickey Sian

Introduction: Langerhans’ Cell Histiocytosis (LCH) is a rare disease, more common in children than in adults, resulting from aberrant proliferation of Langerhans’ cells, belonging to the monocyte–macrophage system.Case history: We present the case report of a 40-year-old man with a 16-year history of polyuria, polydipsia and tiredness. For 10 years he had perianal, groin, abdomen and scalp scarring, hyperpigementation along with follicles ...

ea0025p305 | Steroids | SFEBES2011

Is there a threshold morning cortisol level at which to perform the short synacthen test?

Bujawansa Sumudu , Kunasegaran Shalini , McNulty Steve , Hardy Kevin , Al-jabouri Mohammad , Furlong Niall , Srinivas-Shankar Upendram

Introduction: Short synacthen test (SST) is of value in assessing the adequacy of hypothalamic–pituitary–adrenal axis (HPA). Although it is extensively used, it is unclear at what morning cortisol concentration one should consider performing the SST.Methods: Retrospective observational study of consecutively performed SST (250 μg) between January 2009 and March 2010. Plasma cortisol was measured by enzyme immunoassay (Siemens Advia, Siemen...

ea0021p108 | Clinical practice/governance and case reports | SFEBES2009

Hypoparathyroidism treated with Teriparatide and i.m. vitamin D

Bujawansa Sumudu , Leong King Sun , Leonard Maureen , Wolstenholme Helen , Khalathil Dhanya , Fraser William

Introduction: Hypoparathyroidism is normally treated with calcium salts and activated vitamin D. Here we report a case where synthetic 1–34 PTH (teriparatide) and i.m. vitamin D was successful in treating a case of primary hypoparathyroidism resistant to conventional treatment.Case report: A 16-year girl presented to the emergency department with vacant episodes and mild confusion. Her childhood was uneventful until the age of 12 when she developed ...