Searchable abstracts of presentations at key conferences in endocrinology

ea0084ps2-07-66 | Graves’ Disease 1 | ETA2022

Influence of thyroperoxydase and thyroglobulin antibodies on the presentation and the evolution of medically treated graves’ disease

Matei Constantinescu Stefan , Hospel Julien , Daumerie Chantal , Alexopoulou Orsalia , Maiter Dominique , Burlacu Maria-Cristina

Introduction: Thyrotropin receptor stimulating antibodies (TRAb) are responsible for GravesÂ’ disease (GD) manifestations. Other thyroid antibodies, namely thyroperoxidase (TPOAb) and thyroglobulin (TGAb) antibodies are highly prevalent in GD, but their roles in GD presentation and evolution are controversial.Methods: We retrospectively analysed TPOAb and TGAb levels and evolution in 88 consecutive patients with newly diagnosed GD between 2000 and 20...

ea0049ep1342 | Thyroid (non-cancer) | ECE2017

Immune reaction to food antigens in Graves’disease (GD) patients: role of gliadin and other food antigens

Covelli Danila , Colucci Giuseppe , Salvi Mario , Kaiser Ulrike , Eckstein Anja , Burlacu Maria Cristina , Daumerie Chantal , Richell Gez , Perros Petros , Draman Mohd Shazli , Ludgate Marian , Masetti Giulia , Biscarini Filippo

As known, an imbalance of the gut microbiota is associated with a higher risk for autoimmune diseases. Moreover the increased rates of autoimmunity reported in urban residential areas worldwide suggest a possible influence of diet. We report on the antibody response to food antigens in GD patients. Since 10% of celiac patients develop an autoimmune thyreopathy we focused on gliadin (DGP), transglutaminases (tTG) and 40 other food antigens (FA). Commercially available ELISA ass...