Endocrine Abstracts

Stem cell therapy offers a far-sighted opportunity to cure Type 1 diabetes. To achieve this ambitious goal, an in depth understanding of how human beta cells normally develop is critical, as it provides the perfect model for the differentiation of stem cells down normal safe developmental pathways. Our data provide a framework of human pancreas development and islet formation, highlighting subtle differences from the parallel process in mouse. Key genes have been identified th...