Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1016 | Thyroid (non-cancer) | ECE2013

Evaluation of hemostatic parameters in patients with Hashimoto's thyroiditis

Gorar Suheyla , Bekdemir Handan , Candan Zehra , Culha Cavit , Alioglu Bulent , Aral Yalcin

Introduction: Thyroid dysfunctions and autoimmunity may concur in the pathogenesis of hemostasis abnormalities. HashimotoÂ’s thyroiditis (HT) is a frequently chronic autoimmune disease in thyroid gland. The aim of our study were to comparison the hemostatic parameters in patients with HT and control subjects.Method: A total of 52 women were evaluated. Age, TSH, free T3, free T4, anti M, anti Tg, TAFI, TFPI, PAI-1, tPA, PF-4, fib...

ea0022p635 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

A case of lymphocytic panhypophysitis

Candan Zehra , Koc Gonul , Dellal Dilek , Ucler Serap , Gorar Suheyla , Bekdemir Handan , Culha Cavit , Aral Yalcin

A 44-year-old man with 6 months history of headache, fatique, depressive mood, anorexia, impotence, decreased libido, poliuria and polidypsia. The results of the physical examination were normal, except the patient had noduler guatr. Baseline hormonal investigations and dinamic tests showed panhypopituitarism and partial central diabetes insipidus. Magnetic resonance imaging (MRI) of the pituitary gland showed enlarged pituitary gland and a marked thickening (4.5 mm) of the in...

ea0041ep629 | Endocrine tumours and neoplasia | ECE2016

Circulating levels of survivin in acromegaly

Ademoglu Esra , Candan Zehra , Gorar Suheyla , Niyazoglu Mutlu , Carlioglu Ayse , Yildiz Faruk , Baydar Idris , Sevimli Hakan , Arslan Abdulmuttalib

Introduction: Acromegaly is a chronic disorder characterized by chronic growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in different benign and malignant human tumors. A number of studies showed overexpression of survivin in pituitary adenomas. This study is intended to determine circulating levels of survivin in patients with acr...

ea0022p831 | Thyroid | ECE2010

A difficult case of the medullary thyroid cancer

Dellal Fatma Dilek , Gorar Suheyla , Candan Zehra , Gonenc Anil , Culha Cavit , Koc Gonul , Selim Demir Yavuz , Aral Yalcin

A 49-year-old man with history of nodular goitre operation was referred to our clinic because of MTC in postoperative pathology. He had hypertension, postoperative hypothyroidism, no family history of thyroid carcinoma and sudden death. Laboratuary investigations showed high level of calcitonin (C) (763 pg/ml; normal<150), Carcino embryogenic antigen (CEA) (175 ng/ml; normal<2.5), normal thyroid function tests, parathormone, urinary catecholamines. Ser904 polymorphism ...

ea0041ep524 | Diabetes complications | ECE2016

Is there a tendency for thrombosis in gestational diabetes mellitus?

Gorar Suheyla , Alioglu Bulent , Ademoglu Esra Nur , Uyar Seyit , Bekdemir Handan , Candan Zehra , Saglam Beylan , Koc Gonul , Culha Cavit , Aral Yalcin

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

ea0037ep391 | Diabetes (pathiophysiology &amp; epitemiology) | ECE2015

Lipoprotein associated phospholipase A2 was not associated with diabetic rethinopathy

Candan Zehra , Dellal Fatma Dilek , Dilekci Esranur Ademoglu , Alphan Uc Ziynet , Bekdemir Handan , Koc Gonul , Culha Cavit , Aral Yalcin , Uney Guner , Akkaya Zuleyha Yalniz

Aim: Diabetic rethinopathy is an important microvascular complication in diabetic patients. The association between hyperlipidemia and diabetic rethinopathy remains elusive. Lipoprotein associated phospholipase A2 (Lp-PLA2) is Ca independent serine kinase that hydrolyses oxidized LDL and forms lysilphoshotidylcholine and free fatty acid. The aim of the study was to determine serum levels of Lp-PLA2, traditional lipids, apolipoproteins in patients with diabetic rethinopathy and...