Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1030 | Thyroid (non-cancer) | ECE2016

Acute suppurative thyroiditis caused by burkholderia cepacia

Tarkun Ilhan , Akyay Ozlem Zeynep , Canturk Zeynep , Cetinarslan Berrin , Selek Alev , Catan Fatma Tugba

Introduction: The thyroid is generally resistant to infections due to its encapsulated location, high iodine concentration, hydrogen peroxide production, and high levels of blood and lymphoid circulation therefore acute suppurative thyroiditis is rarely seen. The most common agents are Staphilococcus and Streptococcus. In this case we present acute suppurative thyroiditis caused by Burkholdeira cepacia, that is a rare infectious agent in adults.Case: 34 ...

ea0035p1150 | Thyroid Cancer | ECE2014

BRAF V600E genetic mutation analysis in patients had been diagnosed of unknown malignancy potential thyroid tumors and papillary thyroid microcarcinoma

Sezer Havva , Canturk Zeynep , Ergul Emel , Cetinarslan Berrin

Aim: The purpose of this study was to analysis BRAF V600E mutational status in papillary thyroid microcarcinomas (PTMCs) and unknown malignant potential thyroid tumors (UMP-TTs) and to investigate association of BRAF V600 positivity with clinicopathologic parameters.Material and method: Seventy-two PTMC and 20 UMPTT tissues were included in this study. Genomic DNA was extracted from paraffin-embedded tumor tissue. The paraffin-embedded thyroid tumor samp...

ea0056p695 | Clinical case reports - Pituitary/Adrenal | ECE2018

An acromegaly case; presented from pituitary apoplexia to overt acromegaly before diagnosis

Gonul Burcin , Selek Alev , Cetinarslan Berrin , Canturk Zeynep , Tarkun Ilhan

Pituitary adenomas are the most common lesions of sellar cavity. The usual symptoms are associated with endocrine dysfunctions and mass effects. In this case, a 39 year old female presented with headache for one year and progressive blurred vision, nausea, vomiting for two days. Brain magnetic resonance imaging showed a 16×9 mm hemorrhagic macroadenoma in sellar cavity concordant with apoplexia and anterior pituitary hormone deficiency. The patient underwent transshphenoi...

ea0041ep105 | Bone & Osteoporosis | ECE2016

A rare differential diagnosis of Paget’s disease

Cetinarslan Berrin , Selek Alev , Canturk Zeynep , Tarkun Ilhan , Akyay Ozlem Zeynep , Akkas Nagihan

Hypertrophic osteoarthropathy (HOA) is a syndrome characterized with proliferation of bones at the distal parts of extremities. Clubbing, periostitis of tubular bones and non-inflammatory arthritis of lower extremities are commonly seen as a part of this syndrome.66 years old male patient was admitted to our hospital with painful swelling of his left lower extremity for 2 months. He denies any other systemic symptoms such as fever and weight loss. He had...

ea0041ep1101 | Thyroid cancer | ECE2016

Papillary thyroid carcinoma in a thyroglossal duct Cyst (TDC) without a thyroid primary

Canturk Zeynep , Catan Fatma Tugba , Cetinarslan Berrin , Tarkun Ilhan , Selek Alev , Akyay Ozlem Zeynep

Introduction: Thyroglossal duct cyst (TDC) is a developmental abnormality of the thyroid gland. Malignancy arising from this duct is very rare. Due to embryological remnants of thyroid tissue located in the TDC, all malignant tumors which develop in the thyroid gland may also develop in the TDC. In case of malignancy, the most probable diagnosis is papillary thyroid carcinoma.Case report: We present a 27-year-old female patient complaining of a midline n...

ea0037ep7 | Adrenal cortex | ECE2015

New onset sarcoidosis after remission of Cushing's syndrome

Canturk Zeynep , Selek Alev , Baris Serap , Cetinarslan Berrin , Tarkun Ilhan , Akyay Zeynep

Introduction: Glucocorticoids, even endogenous or exogenous, suppress the inflammatory response therefore they are the most preferred treatment options in inflammatory diseases. Persistent hypercortisolism induces lymphopenia and lymphoid tissue atrophy. Excessive endogenous hypercortisolism might mask the active inflammatory disease. Rebound immune modulation may occur after Cushing’s syndrome (CS) remission, leading to the new onset of autoimmune diseases.<p class="...

ea0037ep722 | Pituitary: clinical | ECE2015

A rare adventure of a lymphocytic hypophysitis

Canturk Zeynep , Selek Alev , Cetinarslan Berrin , Tarkun Ilhan , Akyay Zeynep , Cabuk Burak , Ceylan Savas

Introduction: Lymphocytic hypophysitis is a rare endocrine disease involving lymphocytic infiltration and chronic pituitary inflammation. It may result in significant morbidity by loss of pituitary functions and neurological deficits. Pituitary abscess is another rare disease which may be associated with underlying parasellar pathology. Here, we report a case of lymphocytic hypophysitis diagnosed with a pituitary abscess and recurrent suprasellar involvement after surgery....

ea0037ep760 | Pituitary: clinical | ECE2015

Assessment of mean platelet volume in acromegaly and its relation with disease outcome

Cetinarslan Berrin , Akyay Ozlem Zeynep , Selek Alev , Batman Adnan , Canturk Zeynep , Tarkun Ilhan

Background: Acromegaly is associated with increased risk of coronary atherosclerosis and cardiovascular mortality. Changes in coagulation and fibrinolysis markers in acromegalic patients have been shown to indicate increase in the risk of developing cardiovascular disease. Mean platelet volume (MPV) is a marker of platelet functions and activity, and increased MPV is an independent risk factor of myocardial infarction and thrombotic events. In this study, we examined the level...

ea0037ep761 | Pituitary: clinical | ECE2015

A rare case of papillary thyroid cancer: pituitary metastasis

Akyay Ozlem Zeynep , Cetinarslan Berrin , Tarkun Ilhan , Canturk Zeynep , Selek Alev , Batman Adnan

Introduction: Differentiated thyroid carcinoma (DTC) rarely represents with distant organ metastasis. Cerebral metastasis is seen in 0.4–1.2% of patients with distant organ metastasis. There are only 14 patients of DTC with pituitary metastasis reported in the literature. Here, we report a papillary thyroid carcinoma (PTC) patient represented with pituitary metastasis.Case: A 68-year-old male patient has admitted to our hospital with a growing tumou...

ea0037ep845 | Thyroid cancer | ECE2015

Malignancy risk of thyroid nodules with repeated ‘atypia of undetermined significance/follicular lesion of undetermined significance' diagnosis

Cetinarslan Berrin , Selek Alev , Kivrakoglu Emine , Canturk Zeynep , Tarkun Ilhan , Temiz Duygu , Akyay Zeynep

Introduction: ‘Atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS) is a heterogeneous diagnostic thyroid fine needle aspiration biopsy (FNAB) category. AUS/FLUS is comprised of cases that cannot be definitively diagnosed as benign, suspicious for/consistent with neoplasm, suspicious for malignancy or malignant. The recommended management strategy for these cases is to perform a repeat FNAB after an appropriate time course. A...