Searchable abstracts of presentations at key conferences in endocrinology

ea0032p857 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Similar response to therapy of pituitary adenomas with and without SOX2-expressing cells

Coculescu Mihail , Campean Anca , Stancu Cristina , Capatina Cristina , Livia Gheorghiu Monica , Caragheorgheopol Andra , Hortopan Dan , Ciubotaru Vasile , Raica Marius

Introduction: SOX2 is an early developmental transcription factor and a marker for pituitary progenitor cells.The study aimed to investigate if the pituitary adenomas with positive SOX2 immunoreactivity shows a different response to therapy as compared with controls.Patients and methods: We investigated 15 pituitary macroadenomas, eight with SOX2 immunoreactivity (SOX2+) and seven without (SOX2−) (controls); five were GH prod...

ea0056p864 | Pituitary - Clinical | ECE2018

An immunohistochemical study on pituitary adenomas

Burcea Iulia Florentina , Capatina Cristina , Poiana Catalina

Introduction: Pituitary adenomas (PA) represent approximately 15% of all intracranial neoplasms, with a global incidence of 15,20 per million per year. The immunohistochemical analysis of PA is necessary for diagnosis and plays an important role in the modern classification system of pituitary tumors.Material and methods: Samples from 142 surgically resected PA were studied immunohistochemically using antisera for 6 anterior pituitary hormones. Reticulin...

ea0065p105 | Bone and calcium | SFEBES2019

Complications at diagnosis in primary hyperparathyroidism

Capatina Cristina , Caragheorgheopol Andra , Voicu Gabriela , Poiana Catalina

Introduction: Primary hyperparathyroidism (PHPT) is associated with adverse effects especially on the bones and kidney. While nowadays it is mostly diagnosed at an asymptomatic stage, patients with overt involvement of the target organs at the time of diagnosis are still encountered.Aim: To explore the frequency of disease complications already present at the time of diagnosis in a cohort of patients with sporadic PHPT who meet the current surgical guide...

ea0063p277 | Pituitary and Neuroendocrinology 1 | ECE2019

Gross total versus incomplete resection of craniopharyngioma in adults

Capatina Cristina , Dumitrascu Anda , Caragheorgheopo Andra , Ciubotaru Vasilie , Poiana Catalina

Background: Craniopharyngioma is a rare epithelial tumor of the central nervous system, affecting both children and adults and associated with significant morbidity.Objective: To study the postsurgical evolution of craniopharyngioma in adults after total or incomplete surgical resection.Material and methods: We performed a retrospective review of craniopharyngioma patients evaluated in the National Institute of Endocrinology in Buc...

ea0063p788 | Thyroid 2 | ECE2019

Riedl thyroiditis associated with intense cervical pain

Verdes Andreea , Capatina Cristina , Dumitrascu Anda , Ioachim Dumitru

Introduction: Riedl thyroiditis is a rare thyroid disorder of unknown etiology (autoimmune assumed), in which the gland is invaded by dense fibrous tissue, that extends in the vicinity. Goiter is usually painless and can be accompanied by other fibrous affections (retroperitoneal fibrosis, sclerosing cholangitis, mediastinal fibrosis).Case presentation: Patient, 39 years old, smoker, from nonendemic area, initially presents in 2011 with voluminous polyno...

ea0049ep911 | Neuroendocrinology | ECE2017

Increased morbidity associated with the treatment of craniopharyngioma

Capatina Cristina , Dumitrascu Anda , Caragheorgheopol Andra , Poiana Catalina

Background: Craniopharyngioma is a rare epithelial tumor of the central nervous system, affecting both children and adults and associated with significant morbidity.Objective: To study the posttreatment evolution of craniopharyngioma in children and adults in a large mixed cohort.Material and Methods: We performed a retrospective review of craniopharyngioma patients evaluated in the National Institute of Endocrinology in Bucharest ...

ea0044p153 | Neuroendocrinology and pituitary | SFEBES2016

Clinical and radiological presentation of craniopharyngioma in a mixed cohort of children and adult patients

Capatina Cristina , Bodnarescu Mihaela , Dumitrascu Anda , Caragheorgheopol Andra , Poiana Catalina

Background: Craniopharyngioma is a rare epithelial tumor of the central nervous system, affecting both children and adults and associated with significant morbidity.Objective: To study the potential differences in the clinical and radiological presentation of craniopharyngioma in children versus adults in a large mixed cohort.Material and methods: We performed a retrospective review of craniopharyngioma patients evaluated in the Na...

ea0059p025 | Adrenal and steroids | SFEBES2018

Secondary diabetes mellitus in patients with endogenous cushing’s syndrome

Capatina Cristina , Baciu Ionela , Greere Daniela , Caragheorgheopol Andra , Poiana Catalina

Introduction: Endogenous Cushing’s syndrome (CS) is a rare disease associated with severe morbidity and increased mortality if untreated. Glucose metabolism is significantly altered in hypercortisolism.Objective: To retrospectively analyse the clinical presentation of a cohort of patients with endogenous CS and study the frequency of glucose metabolism abnormalities as opposed to other clinical signs and symptoms.Material and ...

ea0038p379 | Reproduction | SFEBES2015

Testicular regression syndrome and severe psychiatric disorder – a rare association preventing the optimal management of the endocrine condition

Capatina Cristina , Ghinea Adela , Deciu Diana , Poiana Catalina

Introduction: Testicular regression syndrome (TRS) or vanishing testis syndrome is a rare condition defined as the absence of testicular tissue in a genetic and phenotypic male. Rudimentary accessory structures can be present; in that case, the removal of all remnants is recommended.Case report: Male patient, 39 years old, had initially been evaluated at the age of 8 for persistent bilateral cryptorchidism. The medical documents are lacking except for a ...

ea0037gp.11.09 | Calcium, Vitamin D and Bone (1) | ECE2015

Physical performance in women with vitamin D deficiency

Capatina Cristina , Carsote Mara , Berteanu Mihai , Poiana Catalina

Introduction: VD deficiency is associated with the atrophy of muscle fibres (predominantly type II). This leads to decreased muscle force and general physical performance.Objective: To analyse the relationship between the serum concentration of 25-hydroxy vitamin D (25OHD), balance and physical performance in women with VD deficiency and the effect of VD supplementation or treatment with a VD analog.Materials and methods: We analys...