Endocrine Abstracts

A 65-year-old Moroccan man was regularly followed in the outpatient clinic for type 2 diabetes since 2010 and was well controlled with an oral treatment. His past medical history included severe hypertension since 1985. Despite four antihypertensive agents, his blood pressure was not controlled (BP: 220/120 mmHg). A suspicion of renal artery stenosis was excluded by an invasive procedure.He presented an impaired renal function (GFR: 50 ml/min) and his se...

We report on a 50-year-old patient of Moroccan origin, with insulin treated type 2 diabetes known for several years. He presented with a 6 months history of hypoglycemia, hypotension, associated with loss of libido and erectile dysfunction, anorexia, general deterioration and weakness. He had lost 20 kg over a 6-month period. The insulin doses were diminished from 70 to 42 U/day and the antihypertensive treatment was stopped due to repeated episodes of hypotension.<p class...

Introduction: Congenital hypopituitarism may be the result of complications linked with delivery or may sometimes result of insufficient development of the gland in the context of specific genetic abnormalities (PROK2 and PROKR2, LHX4, HESX1, OTX2, GLI2 and SOX3). Interruption or lack of pituitary stalk represents a frequent feature of congenital hypopituitarism.Case description: We present a patient 39-year-old with congenital panhypopituitarism, mental...

Introduction: Cushing’s syndrome (CS) is a medical condition resulting from a chronic excessive exposure to glucocorticoids. ACTH-dependent CS are mostly caused by pituitary adenoma (about 80-85% of the cases) and, in a lower proportion, by ectopic ACTH secretion (about 10-15% of the cases). The exact origin of an ectopic secretion of ACTH is not always easy to identify. The most common locations are bronchus, lung and pancreas but it can also be located ...