Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.23.07 | Thyroid – diagnosis | ECE2015

Immunohistochemical tool for the diagnosis of benign and malignant follicular tumours

Castelblanco Esmeralda , Martinez Montserrat , Santos Ma Dolores , Mancikova Veronica , Robledo Mercedes , Matias-Guiu Xavier , Maravall Javier , Mauricio Didac

Introduction: Follicular tumours of the thyroid gland include benign follicular adenomas, follicular carcinomas and the follicular variant of papillary carcinoma. Although, molecular markers are a promising area of research to differentiate thyroid neoplasms, there is ample room for improvement in the research and clinical applications in this field. Furthermore, the final diagnosis requires thyroid lobectomy. The present study examined whether a differential protein expressio...

ea0035p1095 | Thyroid Cancer | ECE2014

Differential miRNAs expression in papillary thyroid cancer is associated with clinico-pathological features and BRAF mutation

Castelblanco Esmeralda , Rosado Veronica , Martinez Montserrat , Santos Maria Dolores , Mancikova Veronica , Robledo Mercedes , Matias-Guiu Xavier , Maravall Javier , Mauricio Didac

Introduction: MicroRNAs (miRNAs) are short non-coding RNAs that regulate translation or degradation of target mRNAs. Therefore, miRNAs control gene expression in many biological processes, including proliferation, apoptosis, and differentiation. Deregulation of miRNAs expression is an important contributor to tumour development and progression. Even though several genetic and epigenetic lesions have been identified in human thyroid cancer, particularly in the papillary histoty...

ea0056p449 | Diabetes complications | ECE2018

Type 1 diabetes is associated with a differential pattern of carotid atherosclerotic plaque types

Castelblanco Esmeralda , Ramirez-Morros Anna , Hernandez Marta , Granado Minerva , Betriu Angels , Puig-Domingo Manel , Alonso Nuria , Mauricio Didac

Introduction: The presence and type of atherosclerotic plaque is associated with future cardiovascular events (CVE). We previously described that increased frequency of plaques is associated with specific features in type 1 diabetes. The aim of the present study was to investigate the characteristics of atherosclerotic plaques in patients with type 1 diabetes mellitus (T1D).Methods: A cross-sectional study of 174 subjects with carotid atherosclerotic pla...

ea0056p464 | Diabetes complications | ECE2018

Subclinical atheromatous disease detection improves cardiovascular event prediction in chronic kidney disease with and without diabetes

Palanca Ana , Castelblanco Esmeralda , Betriu Angels , Valdivielso Jose M , Perpinan Hector , Puig-Domingo Manel , Fernandez Elvira , Mauricio Didac , Alonso Nuria

Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients with and without diabetes mellitus (DM). Traditional cardiovascular risk factors fail to fully account for the increase in cardiovascular risk in these patients. The NEFRONA study is a large, multicentre, prospective, observational study that evaluated atheromatous disease (AD) in the carotid and femoral territories in a large cohort of Spanish CKD ...

ea0056gp101 | Diabetes Therapy | ECE2018

A healthier fat intake is associated with absence of diabetic retinopathy in patients with type 1 diabetes

Granado-Casas Minerva , Martin Mariona , Real Jordi , Ramirez-Morros Anna , Castelblanco Esmeralda , Alonso Nuria , Traveset Alicia , Alcubierre Nuria , Puig-Domingo Manel , Hernandez Marta , Mauricio Didac

Background: Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetic complications. Our aim was to assess differences in food and nutrient intake of type 1 diabetic patients with and without diabetic retinopathy (DR).Subjects and methods: This was a two-center, cross-sectional study in patients diagnosed with T1DM with and without DR. Su...