Endocrine Abstracts

Objective: Guidelines recommend using fine needle aspiration cytology (FNAC) to guide thyroid nodule surgical indication, however to what extent these guidelines are followed remains unclear. This study aimed to analyze the quality of the preoperative care pathway and the influence of the care pathway on surgical indications relevance.Design: Nationwide historical cohort study based on data from a sample (1/97th) of French health insurance beneficiaries....

Context: Somatostatin receptor type 5 (SST5) is inconsistently expressed by corticotroph tumors, with higher expression found in corticotropinomas having ubiquitin-specific protease 8 (USP8) mutations.Aims: To study the correlation between characteristics of corticotropinomasand SST5 expression/USP8 mutation status; to describe the response to pasireotide in 5 patients.Design: Retrospective cohort study.Metho...

Dysthyroid Optic Neuropathy (DON) is a rare but sight threatening complication of Graves orbitopathy (GO), secondary to optic nerve compression or optic nerve stretching. A previous study from our group showed that medical and surgical treatment of DON according to EUGOGO guidelines resulted in a significant recovery in 70% of DON. However 30% had only partial or no recovery. Teprotumumab is an Insulin Growth Factor -1Receptor inhibitor (IGF-1R) showing impressive results in t...