Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep2 | Adrenal cortex (to include Cushing's) | ECE2016

Effect of heterophilic antibody interference in ACTH immunoassay to Subclinical Cushing’s Syndrome screening: A pilot study

Yener Serkan , Ozisik Seciil , Cavdar Umit , Demirpence Mustafa , Comlekci Abdurrahman

Heterophilic antibodies are well-known interferent factors affecting most immunoassays. However, they have been poorly evaluated in routine clinical practice. Definition of Subclinical Cushing’s Syndrome (SCs) has been arbitrary and prevalence has shown significant variations related with the diversity of the diagnostic tests. In most of the guidelines a low or suppressed corticothropin (ACTH) level has been suggested as an important predictor of SCs. Here, we sought to i...

ea0056p944 | Female Reproduction | ECE2018

Mayer Rokitansky Küster Hauser syndrome: a case report

Aycicek Bercem , Cavdar Umit , Kutbay Nilufer Ozdemir , Diri Halit

Objective: Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) is a very rare congenital anomaly characterised by vaginal agenesis and a spectrum of different genitourinary tract anomalies. Typical form of this syndrome is characterised by congenital absence of the uterus and upper 2/3 vagina with normal ovaries and fallopian tubes and atypical form of the syndrome is associated with anomalies of the ovaries and fallopian tubes and renal anomalies.Case r...

ea0056ep122 | Pituitary and Neuroendocrinology | ECE2018

Clinical improvement of hyperglycemia after use of octreotide lar in a patient with acromegaly who presented with nonketotic hyperosmolar state

Cavdar Umit , Ozdemir Nilufer , Aycicek Bercem , Diri Halit

A 37-year-old patient with a history of transcranial pituitary surgery because of acromegaly was referred to our clinic with the glucose level 731 mg/dl. she was not using any medication. There was no ketone in the urine and HbA1c was 18.6%. She has 17×16×15 mm of residual macroadenoma on pıtuıtary MRI with level of GH 17.5 ng/ml and IGF-1 422 ng/ml. She was using 140 units of insulin glargin U300 and 100 units of insulin regular per a day before octreotide...

ea0041ep28 | Adrenal cortex (to include Cushing's) | ECE2016

Adenoma size could be an important predictor of Subclinical Cushing’s Syndrome

Yener Serkan , Baris Mustafa , Demirpence Mustafa , Ozisik Secil , Cavdar Umit , Demir Omer , Secil Mustafa , Comlekci Abdurrahman

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs.Dokuz Eylul University Adrenal Tumours Study Group database includes 596 patients by January 2016. Briefly, there are 332...

ea0037ep342 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Familial partial lipodystrophy linked to a novel peroxisome proliferator activator receptor-γ mutation, H449L

Demir Tevfik , Onay Huseyin , Savage David B , Kuruuzum Ayse Kubat , Erdeve Senay Savas , Altay Canan , Ozen Samim , Demir Leyla , Cavdar Umit , Akinci Baris

Introduction: Familial partial lipodystrophy (FPL) is a rare genetic disorder characterised by a selective lack of subcutaneous fat that is associated with insulin resistance and diabetes. FPL has been reported to be caused by mutations in the peroxisome proliferator activator receptor-γ (PPARG) gene, which encodes a key transcription factor that regulates adipocyte differentiation and insulin sensitivity.Material and methods: The objective of this ...