Searchable abstracts of presentations at key conferences in endocrinology

ea0070oc2.3 | Bone and Calcium | ECE2020

Prediction algorithm for persistent primary hyperparathyroidism after parathyroidectomy

Repaci Andrea , Vicennati Valentina , Salituro Nicola , Vandi Giulia , Zavatta Guido , Altieri Paola , Di Dalmazi Guido , Gambineri Alessandra , Pelusi Carla , Burgio Luca , Piccin Ottavio , Cavicchi Ottavio , Pagotto Uberto

Background: Primary hyperparathyroidism (PHPT) is characterized by an excessive secretion of the parathyroid hormone (PTH) with normal or high calcium levels. The gold standard therapy involves minimally invasive parathyroidectomy with intraoperative PTH (ioPTH) monitoring. Different criteria have been identified when predicting cure rates using ioPTH values.Objective: To evaluate the percent ioPTH drop (ΔioPTH), the post-excision ioPTH, the first p...

ea0049ep1381 | Thyroid (non-cancer) | ECE2017

BRAFV600E status and Stimulated Thyroglobulin at ablation time increase prognostic value of American Thyroid Association (ATA) classification systems for persistent disease in Differentiated Thyroid Carcinoma (DTC)

Repaci Andrea , Vicennati Valentina , Paccapelo Alexandro , Salituro Nicola , Cavicchi Ottavio , Monari Fabio , Tallini Giovanni , Gruppioni Elisa , Altimari Annalisa , Fiorentino Michelangelo , Pagotto Uberto

Background: Stimulated Thyroglobulin levels measured at the time of remnant ablation (Htg-A) and BRAFV600E mutation were shown to have prognostic value in predicting persistent disease in DTC. The aim of this study was to evaluate the prognostic role of Htg-A combined with BRAFV600E status in association with revised American Thyroid Association (ATA) risk stratification.Patients and methods: 620 patients treated for a DTC were included in this study wit...

ea0081rc3.4 | Rapid Communications 3: Thyroid 1 | ECE2022

Are BRAF-TERT mutated differentiated thyroid cancers similar to other double mutated?

Colapinto Alessandra , Basso Cristina , Vicennati Valentina , Cavicchi Ottavio , Lodi Rizzini Elisa , Golemi Arber , Tabacchi Elena , Nannini Margherita , De Biase Dario , De Leo Antonio , Tallini Giovanni , Pagotto Uberto , Repaci Andrea

Introduction: Differentiated thyroid cancers (DTCs) carrying BRAF and TERT mutations are associated with high-risk clinicopathological features and poor prognosis. However, there are currently no studies comparing BRAF-TERT tumors to other double mutated DTCs.Aim: To verify whether BRAF-TERT mutated DTCs differ from other double mutated DTCs in terms of clinicopathological characteristics and outcome.Materials and Methods: 168 DTCs...

ea0081rc3.5 | Rapid Communications 3: Thyroid 1 | ECE2022

Impact of stimulated thyroglobulin and BRAF status in Stage I and ATA intermediate risk DTC

Basso Cristina , Colapinto Alessandra , Vicennati Valentina , Pagotto Uberto , Tallini Giovanni , De Leo Antonio , De Biase Dario , Lodi Rizzini Elisa , Cavicchi Ottavio , Nannini Margherita , Tabacchi Elena , Golemi Arber , Repaci Andrea

Introduction: There is no clear indication for radioiodine treatment (RAI) in patients affected by differentiated thyroid cancer (DTC) in Stage I and ATA intermediate risk, according to American Thyroid Association (ATA) guidelines.Purpose: Our aim is to evaluate whether integration of BRAF status and thyroglobulin TSH-stimulated at the time of RAI (A-HTg) could further improve accuracy of stratification, and therefore therapeutic management, in DTC pati...