Searchable abstracts of presentations at key conferences in endocrinology

ea0014p155 | (1) | ECE2007

The effect of SOM230 on cell proliferation and cortisol secretion in the human adrenal carcinoma cell line H295R

Mariniello Barbara , Cervato Sara , Opocher Giuseppe , Albiger Nora , Occhi Gianluca , Scaroni Carla , Mantero Franco

Adrenocortical carcinoma (AC) is a rare neoplasm with poor prognosis. Medical treatment of AC is actually based on the use of opÂ’DDD (mitotane) with or without traditional chemotherapeutic agents. Only very few information are available about the effectiveness of somatostatin analogs in AC. In human adrenal gland the expression of all five somatostatin receptor (SSTR) subtypes was previously demonstrated. A differential expression was shown in adrenal adenomas and carcino...