Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep627 | Thyroid | ECE2021

Laser ablation versus radiofrequency ablation for benign non-functioning thyroid nodules: twelve-month results of a randomized, parallel-arm, open-label trial

Cesareo Roberto , Manfrini Silvia , Pasqualini Valerio , Ambrogi Cesare , Sanson Gianfranco , Gallo Andrea , Pozzilli Paolo , Pedone Claudio , Crescenzi Anna , Palermo Andrea

BackgroundRadiofrequency ablation (RFA) seems to achieve a significantly larger nodule volume reduction rate (VRR) than laser ablation (LA) in benign non-functioning thyroid nodules (BNTNs). We compared the efficacy and safety of both thermal ablation treatments at the 12-month follow-up in patients with solid or predominantly solid BNTN.MethodsThis 12-month, single-use, randomized open-label parallel trial c...

ea0070oc7.6 | Endocrine-related Cancer | ECE2020

Llaser ablation vs radiofrequency ablation for benign non-functioning thyroid nodules: six-month results of a randomised, parallel, open-label, trial (LARA trial)

Cesareo Roberto , Maurizio Pacella Claudio , Pasqualini Valerio , Campagna Giuseppe , Lauria Pantano Angelo , Pozzilli Paolo , Cianni Roberto , Manfrini Silvia , Crescenzi Anna , Palermo Andrea

Background: No direct prospective studies comparing laser ablation (LA) and radiofrequency ablation (RFA) for debulking benign non-functioning thyroid nodules (BNTNs) exist. We aimed to compare the efficacy and safety of both techniques in patients with solid or predominantly solid BNTN.Methods: This six-month, single-use, randomized open label parallel trial compared the following primary endpoints between the RFA and LA groups six months after treatmen...

ea0056gp265 | Thyroid non cancer - Benign Thyroid disease/ treatment | ECE2018

Nodule size as predictive factor of efficacy of radiofrequency ablation in treating autonomously functioning thyroid nodules

Palermo Andrea , Naciu Anda Mihaela , Iozzino Mario , Pasqualini Valerio , Simeoni Carla , Manfrini Silvia , Tabacco Gaia , Casini Alessandro , Campagna Giuseppe , Cesareo Roberto

Background: Radiofrequency ablation(RFA) has been advocated as an alternative to radioiodine and/or surgery for the treatment of autonomously functioning benign thyroid nodule (AFTN). However, only a few studies have investigated the efficacy of RFA on AFTN. Furthermore, these studies are characterized by several biases about patient selection, number of RFA treatments, short clinical and radiographic follow-up. A recent prospective 12-month study has demonstrated that one sin...

ea0073aep104 | Calcium and Bone | ECE2021

Evaluation of bone quality by dxa-based bone strain index in primary hyperparathyroidism

Tabacco Gaia , Naciu Anda Mihaela , Messina Carmelo , Rinaudo Luca , Cesareo Roberto , Falcone Stefania , Manfrini Silvia , Napoli Nicola , Bilezikian John , Ulivieri Fabio Massimo , Palermo Andrea

BackgroudPrimary hyperparathyroidism (PHPT) is associated with impaired bone quality and increased fracture risk. Reliable tools for the evaluation of bone quality parameters are not yet clinically available. Bone Strain Index (BSI) is a new metric for bone strength based on Finite Element Analysis from lumbar spine and femoral neck dual X-ray absorptiometry images.AimTo assess the lumbar spine (LS), femoral ...

ea0063gp20 | Calcium and Bone 1 | ECE2019

Clinical, biochemical and radiological profile of normocalcaemic hyperparathyroidism: a multicentric cross-sectional evaluation

Naciu Anda Mihaela , Tabacco Gaia , Falcone Stefania , Santonati Assunta , Maggi Daria , D'Onofrio Luca , Briganti Silvia Irina , Castellitto Domenico , Casini Alessandro , Pedone Claudio , Fabbri Andrea , Napoli Nicola , Pozzilli Paolo , Manfrini Silvia , Cesareo Roberto , Palermo Andrea

Background: The normocalcaemic hyperparathyroidism (NHPT) has been defined as a condition with persistently normal total and ionized calcium levels in the presence of high levels of PTH. The clinical aspects of NHPT have been evaluated in different cohorts but the interpretation of these findings is confounded by differing methods used to rule out secondary hyperparathyroidism and by the small number of NHPT subjects enrolled. Up to now, there is no information available that ...