Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep110 | Bone & Osteoporosis | ECE2016

Clinical characteristics of Paget disease of bone from Turkey

Yavuz Dilek Gogas , Ayturk Semra , Bayraktar Firat , Cetinkalp Sevki , PD Study Group

Prevalence of Paget’s disease (PD) of bone as well as clinical and demographical presentation may differ between the populations.Aim: In this study we evaluate clinical and demographical parameters of Paget’s disease patients followed from endocrinology clinics in Turkey.Method: An invitation was sent to all tertiary endocrinology clinics to complete a survey on demographic clinical, laboratory parameters, treatment modal...

ea0035p73 | Bone and Osteoporosis | ECE2014

Efficacy of zoledronic acid treatment in Paget disease of bone

Baykan Emine Kartal , Saygili L Fusun , Erdogan Mehmet , Ozgen A Gokhan , Cetinkalp Sevki , Yilmaz Candeger

Purpose: Paget disease is a disease of bone of unknown etiology with increased bone turnover that results in defective bone microarchitecture and bone deformity. Bisphosphonates are used in symptomatic Paget disease of bone. Clinical trials have shown that zoledronic acid was more effective than other bisphosphonates in treatment of Paget disease.Methods: In this study, we retrospectively reviewed the remission and relapse statuses of 12 patients with Pa...

ea0035p521 | Endocrine tumours and neoplasia | ECE2014

A case of insulinoma localized in pancreas tail that cannot be monitored with endosonography and abdominal MR but with contrast abdominal BT

Kutbay Nilufer Ozdemir , Ocek Levent , Nart Deniz , Erdogan Mehmet , Cetinkalp Sevki , Ozgen A Gokhan , Saygili Fusun

Introduction: Insulinoma is a rare neuroendocrine tumor. 90% of insulinoma is solitaire and benign, and 10% is malignant. Although seen at any age, it is most commonly noticed in 4th and 6th decades.Case: A 78-year-old man was referred to a neurology clinic upon a sudden faint, disability to remember and meaningless behavior, and diagnosed with epilepsy in 2008. In 2012, he had a hypoglycemia attack (blood glucose 30 mg/dl) and was referred to Ege Univer...

ea0020p118 | Thyroid | ECE2009

Demographic, clinical, laboratory, ultrasonographic and cytological features of patients with Hashimoto’s thyroiditis: results of a university hospital of 769 patients in Turkey

Erdogan Mehmet , Erdem Nihat , Cetinkalp Sevki , Ozgen Gokhan , Saygili Fusun , Yilmaz Candeger , Tuzun Mehmet , Kabalak Taylan

Background: We investigated the demographic and clinical features of patients with Hashimoto’s thyroiditis who had been diagnosed and treated in Ege University, the main referral center in the Aegean region of Turkey.Methods: Medical records of patients who had been followed in the endocrinology clinic of Ege University were retrospectively evaluated. Patients who had been diagnosed as having any thyroid disorder were determined. Patients with Hashi...

ea0020p387 | Diabetes and Cardiovascular | ECE2009

Plasma thrombin-activatable fibrinolysis inhibitor (TAFI) antigen levels in diabetic foot ulcers

Erdogan Mehmet , Solmaz Soner , Canataroglu Abdullah , Kulaksizoglu Mustafa , Cetinkalp Sevki , Ozgen Gokhan , Saygili Fusun , Yilmaz Candeger

Objective: Diabetic foot ulcer is associated with increased morbidity and mortality. The most important factor related to the development of foot ulcer is peripheral neuropathy. Thrombin-activatable fibrinolysis inhibitor (TAFI) is associated with coagulation, fibrinolysis and inflammation. Plasma TAFI may participate in arterial thrombosis in cardiovascular diseases (CVD). TAFI may be involved in the mechanism of vascular endothelial damage in diabetic patients. The aim of th...

ea0041ep102 | Bone & Osteoporosis | ECE2016

A rare cause of hypocalcaemia: pseudohypoparathyroidism

Alp Gulay , Kutbay Nilufer Ozdemir , Yurekli Banu Sarer , Karaca Emin , Erdogan Mehmet , Cetinkalp Sevki , Ozgen Gokhan , Ozkinay Ferda , Saygili Fusun

Introduction: Pseudohypoparathyroidism (PHP) is a rare disease characterized by end-organ resistance to parathyroid hormone, causing hypocalcemia with hyperphosphatemia and elevated parathormone (PTH) levels. A prevalence of 3.4/million has been reported. Here, we present a rare case with PHP.Case report: A 28-year-old male patient with spasms in hands and feet was evaluated in the outpatient department of neurology and was referred to endocrinology clin...

ea0037ep3 | Adrenal cortex | ECE2015

A case of polyglandular autoimmune syndrome type 1 with hypercalcaemia and hypotension

Kutbay Nilufer Ozdemir , Yurekli Banu Sarer , Yaman Miray , Erdogan Mehmet , Cetinkalp Sevki , Saygili Fusun , Darcan Sukran , Ozgen Gokhan

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is also known as autoimmune polyendocrine syndrome type 1 (APS-1). We present a case of autoimmune polyendocrine syndrome type 1 with hypercalcaemia of adrenal insufficiency during the calcium treatment because of hypoparathyroidism.Case: A 20-year-old female patient was diagnosed with APS-1 in 2004. She applied to ER with the complaints of nausea and vomiting. Her laboratory finding...

ea0035p1093 | Thyroid Cancer | ECE2014

Atorvastatin medullar thyroid cancer over TT cell line impact of apoptosis and calcitonin over gene expression

Baykan Emine Kartal , Avci Cigir Biray , Erdogan Mehmet , Cetinkalp Sevki , Ozgen A Gokhan , Gunduz Cumhur , Saygili L Fusun

Medullar thyroid cancer (MTK) approximately constitutes 5% of thyroid cancer, over the 25% cases it progresses in familial form. In charge of genetic inherited clinical features in RET protooncogene ‘germ-line’ makes up activating mutations. In post RET mutation in association with tyrosine kinase activation oncogenic cell proliferation is increased. In medullary thyroid cancer persistent and recurrence disease management is complicated, because it is unresponsive to...

ea0037ep134 | Reproduction, endocrine disruptors and signalling | ECE2015

A case of dyskeratosis congenita associated with hypothyroidism and hypogonadism

Kutbay Nilufer Ozdemir , Erdemir Zehra , Yurekli Banu Sarer , Karaca Emin , Erdogan Mehmet , Cetinkalp Sevki , Kandiloglu Gulsen , Ozgen Gokhan , Ozkinay Ferda , Saygili Fusun

Introduction: Dyskeratosis congenita is a rare multisystemic disease characterised with atrophy on skin, pigmentation, nail dystrophy, leukoplakia in mucous membrane, bone marrow failure, and tendency to malignancy. We present a rare case of dyskeratosis congenita associated with hypothyroidism and hypogonadism.Case: A 30-year-old male patient was referred to Endocrinology Department with the findings of micropenis and atrophic testicles. His parents had...