Searchable abstracts of presentations at key conferences in endocrinology

ea0029p946 | Female Reproduction | ICEECE2012

Inhibin-α gene promoter polymorphisms in patients with idiopathic premature ovarian failure

Yoon S. , Kim J. , Chae S. , Hwang K. , Choi Y\.

Background: Premature ovarian failure (POF) is a complex disorder defined as the cessation of ovarian function before or at the age of 40. Although the etiology of POF remains unknown in a large proportion of cases, it has been suggested that variations in the Inhibin α gene (INHA) may affect the ovarian function of women. This study was performed to investigate whether the genetic polymorphisms of the INHA gene are associated with idiopathic POF in a Korean population.</...

ea0029p1616 | Thyroid (non-cancer) | ICEECE2012

A possible common link between Graves’ disease and allergic immune response

Kim H. , Kim S. , Chae J. , Kim D. , Baek S. , Won K. , Sung Y.

Background: The elevation of serum immunoglobulin E (IgE) has been recently reported to be associated with Graves’ disease (GD). Interleukin 13 (IL-13) is a major cytokine involved in IgE synthesis and therefore may be a potential candidate gene influencing the clinical course of the GD. The aim of this study are to evaluate whether the atopic parameter such as total IgE is related to TSH receptor antibody (TRAb, thyrotropin-binding inhibitory immunoglobulin: TBII) and wh...