Searchable abstracts of presentations at key conferences in endocrinology

ea0077p224 | Neuroendocrinology and Pituitary | SFEBES2021

Three cases of metastatic spinal cord compression secondary to malignant pheochromocytoma and paraganglioma

Khan Amber , Kapoor Ashutosh , Manoharan Prakash , Chander Amarjot , Westwood Thomas , Woolf David , Hoong Ho Jan , Adam Safwaan

Approximately 15-20% of phaeochromocytomas and paragangliomas (PPGL) are metastatic. Metastatic spinal cord compression (MSCC) has been reported infrequently. We present three cases of MSCC secondary to metastatic PPGLs. MSCC can occur in patients with PPGLs and should be considered in patients with either spinal symptoms or spinal metastases on imaging. Our series has shown radiotherapy followed by therapeutic MIBG to be effective in treating spinal metastases. Each case shou...

ea0087oc3 | Oral Communications | UKINETS2022

Outcomes in patients with advanced well-differentiated gastroenteropancreatic neuroendocrine tumours receiving PRRT early versus later

Robinson Matthew D , Chander Amarjot , Westwood Tom , Manoharan Prakash , Mansoor Was , Lamarca Angela , A Hubner Richard , W Valle Juan , G McNamara Mairead

Background: Neuroendocrine tumours (NETs) are rare malignancies; over 60% of primary lesions arise in the gastrointestinal tract and pancreas. Despite several practice-changing clinical trials, uncertainty persists around the most efficacious treatment sequence in patients with advanced well-differentiated gastroenteropancreatic (GEP) NETs, particularly in relation to peptide receptor radionuclide therapy (PRRT). This study aimed to investigate the progression-free survival (P...

ea0072p10 | (1) | UKINETS2020

Are outcomes of patients with advanced well-differentiated GEP-NETs on somatostatin analogues similar, irrespective of tracer uptake on 68gallium DOTA SSTR peptide PET CT scans?

Shah Dinakshi , Loveland Oliver , Chander Amarjot , Westwood Tom , Manoharan Prakash , Mansoor Was , Lamarca Angela , Hubner Richard A , Valle Juan W , McNamara Mairead G

Background: Neuroendocrine tumours (NETs) are a rare and heterogeneous group of neoplasms that mainly originate from the gastroenteropancreatic tract (GEP-NETs). The vast majority of NETs tend to overexpress somatostatin receptors (SSTRs), which can be targeted by somatostatin analogues (SSAs). 68Gallium DOTA SSTR peptide positron emission tracer computed tomography (68Ga PET-CT) has emerged as superior to other imaging modalities in identifying SSTRs. Th...