Searchable abstracts of presentations at key conferences in endocrinology

ea0014p32 | (1) | ECE2007

Effects of rosiglitazone (RGZ) and pioglitazone (PGZ) on serum androgens and urinary steroid profile in patients with type 2 diabetes: A prospective, randomised cross-over study

Chappuis Bernard , Braun Monika , Stettler Christoph , Diem Peter , Christ Emanuel

Background: Glitazones (GZ) influence androgen biosynthesis in PCO syndrome. At present it is unknown whether a) steroid hormone metabolism is influenced by GZ in patients with type 2 diabetes b) there is a differential effect of RGZ and PGZ on steroid hormone metabolism c) this effect is sex-specific and d) this effect is mediated by changes in insulin sensitivity. Therefore, urinary steroid profiles and serum total testosterone and DHEA levels were analysed before and after ...

ea0014p104 | (1) | ECE2007

Bone density in patients with non-functioning pituitary adenomas (NFA)

Fischli Stefan , Stettler Christoph , Sahli Rahel , Schwab Silvia , Chappuis Bernard , Jenni Stefan , Diem Peter , Christ Emanuel

Background: Surgically treated patients with NFA often present with secondary hypogonadism. Hypogonadism is a well known risk factor for osteopenia or osteoporosis. The aim of this study was to assess (a) the frequency of osteopenia/osteoporosis in a single centre Swiss cohort of patients with operated NFA and (b) whether gender or hypogonadism impacts on bone density at follow up.Methods: Data of patients with NFAs diagnosed between 1967 and 2005 were a...