Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep20 | Adrenal and Neuroendocrine Tumours | ECE2019

Adrenocortical carcinoma: epidemiological, clinical and paraclinical profile: about 4 cases

Mnif Fatma , Elleuch Mouna , Sahnoun Randa , Saafi Wiem , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abud Mohamed

Introduction: The adrenocortical carcinoma (ACC) is a primary malignant tumor developed in depends of the adrenal cortex, defined by a Weiss score ≥3. Despite the therapeutic progress, its prognosis is still severe.Patients and methods: This retrospective descriptive study evaluated 4 patients with adrenal corticosteroid followed in the endocrinology department of Sfax - Tunisia between 2010 and 2018.Results: There were 3 wom...

ea0063p1097 | Pituitary and Neuroendocrinology 3 | ECE2019

Predictive factor of hypopituitarism in prolactinoma

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abid Mohamed

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

ea0063p844 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Association of neurofibromatosis type 1 and neuroendocrine tumor

Kacem Faten Hadj , Zargni Asma , Mnif Fatma , Rekik Fatma , Elleuch Mouna , Salah Dhouha Ben , Charfi Nedia , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Pheochromocytoma occurs in 0.1–5.7% of patients with Neurofibromatosis type 1(NF1). We report two cases of adrenal pheochromocytoma in patients with NF1.Observation: A 46 year-old male was admitted to our department for further examinations of an adrenal mass. The CT-scan showed two well-defined right adrenal masses measuring each 128×87×86 mm and 60×52×37 mm with central necrosis and calcifications in the biggest o...

ea0063p848 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Synchronous tumours: Neuroendocrine Tumours and Breast cancer

Mnif Fatma , El Arbi Kawthar , Hadj Kacem Faten , Zargni Asma , Elleuch Mouna , Ben Salah Douha , Charfi Nedia , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction:: The association of breast cancer and neuroendocrine tumours, in particular pheochromocytoma, is rarely described in the literature. We report a case in a particular context.Observation: This is a 53-year-old patient treated with 6 courses of chemotherapy for T2N3cM0 infiltrating breast carcinoma. She was admitted to our endocrinology department for exploration of a left adrenal incidentaloma, objectified in the extension assessment, measur...

ea0063p1053 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma and elderly subject: which caracteristics?

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Safi Wajdi , Zargni Asma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Rekik Nabila , Charfi Nedia , Abid Mohamed

Introduction: Prolactinoma is the most common secretory pituitary adenomas. It has clinical and biological characteristics that depend on age, gender and tumor size. Prolactinoma of the old subject is a rare clinical form that was not sufficiently treated in the literature.Materiels and methods: It is a retrospective study including 77 cases of prolactinoma among which 3 cases aged over than 65 years. The collection of data was made between 2000 and 2017...

ea0063p1100 | Pituitary and Neuroendocrinology 3 | ECE2019

Outcome of prolactinoma during pregnancy

Elleuch Mouna , Loukil Fatma , Salah Dhouha Ben , Sahnoun Randa , Charfi Nedia , Mnif Fatma , Hadjkacem Faten , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Infertility is a classic consequence of prolactinoma in women. The treatment of hyperprolactinemia allows the restoration of ovulatory cycles and therefore of fertility in 80–90% of cases.Methods and materials: The study is a retrospective cohort study done over 17 years from 2000 to 2017. It includes 77 cases of prolactinomas among which 12 women had one or more pregnancies after the diagnosis of prolactinoma.Re...

ea0073aep197 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Maternally inherited diabetes and deafness, associated with a novel mitochondrial mutation, complicated by sever hypertriglyceridemia: Case report

Rekik Nabila , Gherissi Wiem , salah Dhoha Ben , Salah Ameni , Mnif Mona , Mnif Fatma , Hadjkacem Faten , Charfi Nedia , Elleuch Mona , Abid Mohamed

IntroductionMitochondrial diseases are a clinically heterogeneous group of disorders that arise as a result of dysfunction of the mitochondrial respiratory chain.it is genetically heterogeneous diseases characterized by multisystem involvement. Thus, its clinical description is incomplete. The aim of this case report is to highlight the association between mitochondrial diabetes and severe hypertriglyceridemia. In this study, we describe the case of a 22...

ea0073aep362 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Clinical features of patients with diabetic ketoacidosis and acute pancreatitis

Salah Dhouha Ben , Zargni Asma , Elleuch Mouna , Gherissi Wiem , Mnif Fatma , Charfi Nedia , Mnif Mouna , Majdoub Nabila Rekik , Faten Hadj Kacem , Mohamed Abid

IntroductionAcute pancreatitis (AP) is the most common affection of the pancreas, it often leads to glycemic disorders. On the other hand, diabetic ketoacidosis (DKA) is associated with nonspecific increase in serum amylase levels. The aim of this study was to evaluate the clinical characteristics of acute AP concomitant with DKA.MethodsWe conducted a retrospective and descriptive analysis of clinical records...

ea0073ep133 | General Endocrinology | ECE2021

Severe hypertriglyceridemia in young adults

Gherissi Wiem , Kacem Faten Hadj , Ben Salah Dhoha , Zargni Asma , Mahjoub Rkik Nabila , Mnif Mona , Mnif Fatma , Charfi Nedia , Elleuch Mona , Abid Mohamed

IntroductionSevere hypertriglyceridemia (sHTG) (plasma triglycerides b 10 g/l) is a rare but pernicious and understudied condition.ObjectiveOur objective was to evaluate the etiology, characteristics, and complications of sHTG.MethodsIt’s a retrospective study including 10 patients with (sHTG) diagnosed between 1998 and 2020, at the department of endocri...