Searchable abstracts of presentations at key conferences in endocrinology

ea0014p210 | (1) | ECE2007

Effects of physiological bell-shaped elevations of free fatty acids on glucose metabolism and insulin sensitivity in humans

Gormsen Lars , Nielsen Charlotte , Jessen Niels , Vestergaard Esben , Christiansen Jens , Jørgensen Jens , Møller Niels

Background: Physiological elevations of free fatty acids (FFAs) occur in a dynamic bell-shaped fashion lasting some hours, e.g. nocturnally and during exercise. In order to define the metabolic role of physiological elevations in relation to diurnal fluctuations in insulin sensitivity, the present study was designed to identify the metabolic effects of a dynamic 4 hour elevation of FFAs during a glucose clamp.Materials and methods: 8 lean, healthy men we...