Searchable abstracts of presentations at key conferences in endocrinology

ea0011p698 | Reproduction | ECE2006

Functional restoration of intact rabbit ovary after cryopreservation and transplantation

Chen C , Chen S , Wu G

Objective: Ovarian cryopreservation is an emerging technique that may advance breeding of endangered species and preservation of reproductive capacity in young women cancer patients who will undergo chemo/radiotherapy destruction of ovarian tissue.Materials and methods: A total of twelve mature female rabbits were used in experiment. Rabbits were anesthetized and then subjected to laparotomy. Bilateral oophorectomy was used to save one ovary as fresh con...

ea0036oc6.6 | Oral Communications 6 | BSPED2014

Comparison of type 1 diabetic control before and 5 years after transfer to adult services: audit of the 2008 cohort from the Royal Hospital of Sick Children (RHSC), Glasgow

Wang Jessie R , Chen S Ching , Robertson Kenneth J

Background: Within the NHS Greater Glasgow and Clyde (GGC), many children with type 1 diabetes mellitus (T1DM) are looked after at the RHSC until the age of 16 years, after which they are transferred to their local adult diabetes services. This is the first longitudinal audit within the GGC looking at the changes in diabetic control of the patient pre-and post-transfer.Method: A cohort of 75 patients referred onto the adult diabetes service from RHSC in ...

ea0029p310 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Alterations of protein expression profiles in 3T3-L1 adipocytes by interleukin 4

Chang Y. , Chen S. , Chiu Y. , Tsao C. , Shiau M.

Obesity, characterized by excess intra-abdominal adipose tissue, is closely associated with a cluster of metabolic disorders such as type 2 diabetes mellitus (T2DM). Our previous study revealed significant associations between interleukin 4 (IL4) genotypes and T2DM, as well as IL4 genotypes and high density lipoprotein-cholesterol levels. Our most recent study results reveal that IL4 has anti-hyperglycemic function by improving insulin sensitivity and glucose tolerance. In add...

ea0026p3 | Adrenal cortex | ECE2011

MicroRNAs as endogenous modulators of glucocorticoid receptor expression in the adrenal gland after ACTH stimulation test

Hill A , Issler O , Spyroglou A , Haramati S , Chen A , Beuschlein F

MicroRNAs (miRs) are a subset of small RNA molecules that regulate gene expression post-transcriptionally. Little is known about the expression and the role of miRs in the adrenal gland. Thus, we determined the miRs expression pattern under baseline conditions and 10, 30 and 60 min after ACTH stimulation test in mice adrenal glands using miRs microarray. The miRs expression profile of adrenals obtained from the array was bioinformatically analyzed to indentify miRs that putati...