Searchable abstracts of presentations at key conferences in endocrinology

ea0020p178 | Endocrine tumours and neoplasia | ECE2009

Predictive value of interleukin-10 promoter genotypes and haplotypes in determining the susceptibility to nephropathy in type 2 diabetes patients

Mtiraoui Nabil , Ezzidi Intissar , Chieb Molka , Kacem Maha , Mahjoub Touhami , Almawi WassimY

Background: The IL-10 promoter polymorphisms −1082G/A, −819C/T, and −592C/A have been consistently associated with type 2 diabetes (T2DM). We examined whether these polymorphisms variants are also associated with progression of diabetic nephropathy (DN).Methods: These promoter variants were genotyped in 917 T2DM patients comprising 515 DN patients and 402 control patients without nephropathy (DWN), together with 748 non-diabetic control...