Searchable abstracts of presentations at key conferences in endocrinology

ea0020s26.1 | Thyroid, Pregnancy and Fertility | ECE2009

Thyroid disorders, infertility and miscarriages

Chiovato Luca

Before and during pregnancy the thyroid gland and gonadal axes interact continuously. During reproductive life, normal levels of thyroid hormones are required for the maturation of oocytes. Hypothyroidism influences ovarian function by decreasing levels of sex-hormone-binding globulin and increasing the secretion of prolactin. In women of reproductive age, L-thyroxine therapy reverses hypothyroidism improving fertility and avoiding the need for use of assisted r...

ea0056s1.2 | Predicting events in autoimmune thyroid diseas | ECE2018

IgG4 related thyroid autoimmune disease

Chiovato Luca

IgG4-related disease (IgG4-RD) is a fibro-inflammatory, immune-mediated, systemic disease usually presenting with tumefactive lesions and a subacute onset mimicking malignancy. A subset of autoimmune thyroid pathologic conditions can be incorporated in the spectrum of IgG4-RD. In some cases of Hashimoto’s Thyroiditis (HT) a rich IgG4-positive plasma cell infiltration has been described, and a marked storiform fibrosis is typical of the fibrotic variant of HT (FVHT) and of...

ea0056p1024 | Thyroid (non-cancer) | ECE2018

Post partum and non-post partum relapsing Graves’ hyperthyroidism display different response to anti-thyroid drugs

Capelli Valentina , Rotondi Mario , Coperchini Francesca , Pinto Sara , Croce Laura , Tonacchera Massimo , Chiovato Luca

Background: Graves’ disease (GD) female patients in remission after a full course of methimazole (MMI) therapy are at risk for a relapse of hyperthyroidism during the post-partum (PP) period, but whether this relapse may display any peculiarity is still unknown.Aim: To compare GD patients undergoing a relapse of hyperthyroidism either in the PP period or not.Subjects and methods: Fourty-three female patients of childbearing ag...

ea0022p626 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Longitudinal combined evaluation of antipituitary antibody titer and immunofluorescence pattern is a suitable tool in predicting autoimmune hypophysitis in patients with autoimmune polyendocrine syndromes

Pane Elena , Rotondi Mario , Colella Caterina , Iacovo Assunta Dello , Mora Liliana Dalla , Bellastella Giuseppe , Sinisi Antonio Agostino , Bizzarro Antonio , Chiovato Luca , Bellastella Antonio , De Bellis Annamaria

Antipituitary antibodies (APA) are frequently present in patients with autoimmune polyendocrine syndrome (APS) but their role in predicting autoimmune hypophysitis (LYH) is still discussed.To evaluate the predictive value of APA investigated by immunofluorescence for the occurrence of pituitary autoimmune dysfunction when considering together some methodological characteristics as immunostaining pattern and antibody titers, we studied 149 APA positive an...