Searchable abstracts of presentations at key conferences in endocrinology

ea0055p41 | Poster Presentations | SFEEU2018

A not so sweet glucagonoma

Tan Si Han , Chong Zhuo Min , Howat Isabel

Case history: This 33-year old Scottish female presented in February 2017 with a 3-month history of vomiting, erythematous vesicular pruritic rash and three stone weight loss. The rash started 1 day postpartum in January 2015 and migrated from dorsum of feet to both lower legs, upper thigh and torso. A negative biopsy for pemphigus led the team to suspect necrolytic migratory erythema (NME) in November 2016. Her past medical history includes gestational diabetes with her third...

ea0077p26 | Bone and Calcium | SFEBES2021

Pre-antiresorptive therapy dental screening (PADS): a successful intervention against medication related osteonecrosis of the jaws (MRONJ)

White Gillian , Hughes Caitlin , Burnside Lesley , Munro Robin , Chong Zhuo Min

Introduction: MRONJ is defined as exposed bone in the maxillofacial region that persists after eight weeks in patients treated with antiresorptive or anti-angiogenic drugs, without previous radiotherapy. The estimated United Kingdom incidence of MRONJ in osteoporosis patients is 0.01-0.1% (1). MRONJ can cause severe disfigurement, speech and feeding difficulties. We aim to investigate MRONJ incidence and utility of dental screening in patients receiving Zoledronate ...

ea0065oc3.2 | Bone and Calcium | SFEBES2019

Hypophosphatasia in adulthood - are patients really ‘unaffected’

Chong Zhuo Min , Toellner Hannah , Sainsbury Christopher AR , Srivastava Rajeev , Gallacher Stephen J , Ahmed Syed Faisal

Introduction: Hypophosphatasia (HPP) is a very rare systemic musculoskeletal disease characterised by low tissue non-specific alkaline phosphatase (ALP). The prevalence of HPP and its associated morbidity in an adult setting is unclear.Methods: A search for serum ALP results less than 36 IU/l within NHS Greater Glasgow and Clyde between 2017 and 2018 revealed 16 280 results. A further search for patients with two ALP <36 separated by 30 days or more ...

ea0065p111 | Bone and calcium | SFEBES2019

Hypophosphatasia in an infant: a differential diagnosis that should not be overlooked

Toellner Hannah , Chong Zhuo Min , Srivastava Rajeev , McNeilly Jane , Koppel David , Sangra Meharpal , Shaikh Guftar , McDevitt Helen , Mason Avril , Kinning Esther , Ahmed Syed Faisal

Introduction: Hypophosphatasia is a very rare inherited condition due to ALPL variants and is associated with a variable presentation.Case description: The index case initially presented at 7 months with bulging anterior fontanelle, failure to thrive and mild developmental delay. She was born at 34 weeks gestation and had amniotic bands causing digital anomalies. She was sitting at 8 months, crawling by 15 months and a hearing test was normal. A...