Endocrine Abstracts

Background: The mechanisms regulating adrenarche have not been elucidated, although evidence supports a critical role for ACTH and possibly other unidentified pituitary or adrenal contributing factors. Absent adrenarche has been described in children with a variety of sellar tumors. We describe a case series of five adults with congenital hypopituitarism and absent adrenarche.Cases: Three females and two males with “idiopathic” congenital hypop...