Searchable abstracts of presentations at key conferences in endocrinology

ea0016gh1 | The Geoffrey Harris Prize Lecture | ECE2008

From Geoffrey Harris’s hypothalamic principle to a unified theory of stress and stress system disorders

Chrousos George P

The existence of the principle of hypothalamic hypophysiotropic factors, predicted so prophetically by G W Harris in the 1940’s, has been confirmed by irrefutable evidence. This principle is central to the survival of complex organisms as both individuals and species. Life exists through maintenance of a complex dynamic equilibrium, or homeostasis, that is constantly challenged by intrinsic or extrinsic adverse forces, or stressors. Thus, stress is defined as a state of t...

ea0016gh1biog | The Geoffrey Harris Prize Lecture | ECE2008

Geoffrey Harris Prize Lecture

Chrousos George P

This prestigious prize is intended for established workers in the field of basic or clinical neuroendocrinology, and is generously support by Ipsen. This year's recipient is Professor George P Chrousos. The prize will be presented as part of the ECE 2008 opening ceremony where Professor Chrousos will deliver his lecture. Professor Chrousos will also give two other lectures at future ESE scientific meetings. Further information can be found at <a href="http://www...

ea0056p918 | Female Reproduction | ECE2018

Young lean women with evidence of both premature adrenarche and pubarche display a metabolic, hormonal and psychologic profile that is similar to that of their peers with polycystic ovary syndrome

Livadas Sarantis , Bothou Christina , Kanaka-Gantenbein Christina , Chiotis Dimitrios , Angelopoulos Nicholas , Macut Djuro , Chrousos George P.

Context: The early activation of adrenal zona reticularis, denoted by increased circulating levels of adrenal androgens before the age of eight years in girls is called premature adrenarche (PA), while the concomitant appearance of pubic hair is termed premature pubarche (PP). Girls with PA-PP display an unfavorable metabolic, hormonal and psychologic profile, compared to their normal peers and are also at an increased risk of developing polycystic ovary syndrome (PCO...

ea0063p963 | Diabetes, Obesity and Metabolism 3 | ECE2019

Delayed menarche, oligomenorrhea and hyperandrogenism in type 1 diabetes mellitus

Paschou Stavroula A , Vryonidou Andromachi , Melissourgou Marina , Kosteria Ioanna , Anagnostis Panagiotis , Goulis Dimitrios G. , Chrousos George P , Kanaka-Gantenbein Christina

Aim: To investigate reproductive function disorders in young women with type 1 diabetes mellitus (T1DM).Patients and methods: We studied 53 women with T1DM (duration 8.0±5.6 y) and 51 healthy controls with normal menstrual cycles and no clinical hyperandrogenism, matched for age (19.4±4.3 vs 20.8±3.1 years, P=0.063) and body mass index (BMI) (22.2±2.7 vs 21.4±1.9 kg/m2, P=0.088). T1DM (insulin regimen...

ea0020p474 | Obesity and Metabolism | ECE2009

The evaluation of the oxidative stress in obese adolescent girls with full or partial metabolic syndrome

Karamouzis Ioannis , Kanaka-Gantenbein Christina , I Pervanidou Panagiota , Magiakou Maria-Alexandra , Haidich Anna-Betina , Sakka Sofia , Papasotiriou Ioannis , Chrousos George P

Background: Studies in adults have clearly demonstrated that obesity is a main factor implicated in increased oxidative stress and platelet activation, both predisposing factors for cardiovascular disease leading to increased morbidity and mortality. Furthermore, the metabolic syndrome (MetS), the clustering of abnormalities, such as central obesity, dyslipidemia, impaired glucose tolerance and hypertension, which is an important cardiovascular risk factor in adults, is also h...