Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep151 | Thyroid | ECE2019

Multicentric papillary thyroid carcinoma with concomitant rare dedifferentiation in the lymph node metastasis

Ciobotar Mihaela , Teusan Teodora , Preda Cristina , Ciobanu Delia , Piciu Doina , Leustean Letitia

Introduction: Papillary thyroid carcinoma (PTC) is a differentiated thyroid carcinoma accounting for approximately 80% of all thyroid malignancies; in contrast only 1–2% of thyroid cancers are anaplastic. While the transformation of papillary thyroid carcinoma to the more aggressive anaplastic carcinoma represents a well known occurrence, the transformation of metastatic PTC in a distant location is an uncommon finding, but new insights from the BRAF(V600E) mutat...

ea0041ep790 | Obesity | ECE2016

Micronutrients status in bariatric patients-middle term follow-up for Sleeve Gastrectomy

Hristov Ioana , Mocanu Veronica , Labusca Luminita , Zugun-Eloae Florin , Ciobanu Delia , Timofte Daniel

Introduction: Sleeve gastrectomy is a highly effective bariatric technique for morbidly obese patients thus nutritional deficiencies resulting need routine screening for proper evaluation.Aim: Little is still known about the nutritional side-effects for this restrictive bariatric procedure and our study aims to evaluate the impact of sleeve gastrectomy on micronutrients status.Methods: Our prospective study included 48 morbidly obe...

ea0037ep996 | Thyroid (non-cancer) | ECE2015

Ultrasound-guided fine-needle aspiration biopsy is an efficient diagnostic tool in thyroid nodules

Armasu Ioana , Ciobanu Delia , Istrate Andra , Vasiliu Ioana , Ionescu Lidia , Preda Cristina , Mogos Voichita , Vulpoi Carmen

Introduction: Thyroid nodules are commonly encountered in clinical practice, the main diagnostic problem being the benign or malignant nature of the nodules. Fine-needle aspiration biopsy (FNAB) is a standard diagnostic test for evaluating thyroid nodules. Several studies have showed that the use of ultrasound guidance (US-FNAB) improves the diagnostic accuracy of aspiration biopsies in comparison with palpation guidance (P-FNAB) alone.Patients and metho...

ea0037ep1318 | Clinical Cases–Thyroid/Other | ECE2015

Is thymectomy a solution for myasthenia gravis associated with autoimmune thyroid diseases?

Vasiliu Ioana , Bodescu Ioana , Stefanescu Cipriana , Ciobanu Delia-Gabriela , Ionescu Lidia , Serban Ionela Lacramioara , Vulpoi Carmen

Myasthenia gravis (MG) and autoimmune thyroid diseases (AITD) may coexist and influence one another clinical expression. The opportunity of thymectomy in this association is controversial, since not all the studies have proven its efficacy. We report eight patients (one man and seven women) diagnosed with AITD (Graves’ disease (GD) – five cases, Hashimoto’s thyroiditis (HT) – three cases) and MG. The AITD diagnosis preceded (two cases), followed (three case...

ea0070ep490 | Thyroid | ECE2020

Solitary fibrous tumour of the thyroid, features of a very rare tumour: A case report

Dumitru Teodora , Hrisa Anamaria , Nechita Mirela-Claudia , Ciobanu Delia , Danila Radu , Ungureanu Maria-Christina

Introduction: Solitary fibrous tumor (SFT) is a sporadic tumor, commonly found in the pleural cavity. It is like a large well-circumscribed mass, arising from mesenchymal tissue, with spindle cells proliferation, arranged in various patterns. SFT of the thyroid is exceptionally rare, with only about 28 cases being reported in the international literaterature.A 34-year-old woman presented in the Department of Endocrinology with the diagnosis of a multinod...

ea0022p803 | Thyroid | ECE2010

Thyroid lymphoma: a rare pathology: study on 9 cases

Mogos Voichita , Vulpoi Carmen , Burlacu Cristina , Cotea Elena , Niculescu Dan , Florea Niculina , Ciobanu Delia , Ferariu Dan

Thyroid lymphoma accounts for less than 5% of thyroid malignancies. The aim of this study was to analyze the particularities of 9 patients (7 females and 2 males, aged 42 to 76 years) diagnosed with thyroid lymphoma, representing 2.45% of 340 cases of thyroid malignancies. Patients were assessed by ultrasound examination (7 cases), fine needle biopsy (FNB) (8 cases), lymph node biopsy (2 cases), and histological examination after surgery (7 cases). Clinically, 6 cases presente...

ea0022p809 | Thyroid | ECE2010

Pitfalls in calcitonin measurement: case report

Vasiliu Ioana , Ciobanu Delia , Ungureanu Didona , Balcan Roxana , ElMekkaoui Safae , Idriceanu Jeanina , Mogos Voichita , Vulpoi Carmen

Calcitonin (CT) is a sensitive marker for medullary thyroid carcinoma, but its routine measurement in patients with thyroid nodules is a controversial issue. Generally, an elevated serum calcitonin strongly suggests the presence of medullary thyroid carcinoma (MTC); however high CT levels may be found in other thyroid or non-thyroidal conditions. We report the case of a 49-year-old woman who consulted at the ambulatory of endocrinology for recent thyroid soreness. Biological f...

ea0020p168 | Thyroid | ECE2009

Unsual onset of subacute thyroiditis

Stoica Ioana , Plesa Alina , Ciobanu Delia Gabriela , Dinu Roxana , Zbranca Eusebie , Vulpoi Carmen

Subacute thyroiditis (SAT) is a self-limited inflammatory disease of presumed viral etiology, characterized by pain and thriphasic functional thyroid evolution. We report the case of an 54-years-old woman hospitalized in 02.2008 at the Gastroenterology Department for fever, diahreea, significant weight loss (5 kg in one month), with the suspicion of Crohn’s disease (CD). Two weeks before she presented a subfebrile episode with bilateral jugular lymphadenopathy, dysphagia,...

ea0016p795 | Thyroid | ECE2008

Graves’ disease and myasthenia gravis: who comes first?

Vulpoi Carmen , Andriescu Lidia , Ciobanu Delia Gabriela , Ungureanu Maria Christina , Cuciureanu Dan , Grigoras Mihai , Zbranca Eusebie

Graves’ disease (GD) and myasthenia gravis (MG) may be associated and influence one another clinical expression. We report the cases of 3 female patients who presented this particular association. First patient (RL, 55 years), was diagnosed with MG and, 5 years after, developed GD, remitted after 2 years of anti-thyroid drugs (ATD). She is still euthyroid after more than 10 years, and MG is compensated with moderate doses of anticholinesterase drugs (ACD). Thoracic CT sho...

ea0049ep188 | Endocrine tumours and neoplasia | ECE2017

An elevated chromogranin A: is it always a tumor progression?-case report

Bursuc Anamaria , Daniela Belceanu Alina , Armasu Ioana , Tirnovan Mirela , Manolachie Adina , Crumpei Felicia , Ciobanu Delia , Leustean Letitia , Vulpoi Carmen

Introduction: Pancreatic neuroendocrine tumors (PNET) are rare, with an incidence of 1/100,000/year. Chromogranin A (CgA) is the most valuable marker in the diagnosis and monitoring of PNET. One of the disadvantages is its low specificity and the existence of a number of processes leading to an increase in its concentration, which often results in confusion and diagnostic difficulties.Case report: We present a 44-years-old female patient...