ea0086oc5.3 | Metabolism, Obesity and Diabetes | SFEBES2022
Anthony Amarah
, Clarke George
, Schiffer Lina
, Fan Yiyu
, Hawley James
, Shaheen Fozia
, Hann Angus
, Taylor Angela
, Afford Simon
, Arlt Wiebke
Background: In women, androgen excess is associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). Androgen precursors are released from the adrenal gland and converted to active androgens in peripheral tissues including adipose tissue. Although the liver plays a key role in all metabolic processes in the body, its involvement in androgen metabolism is yet to be explored. Here, we describe the investigation of androgen metabolism in human liver using norm...