Endocrine Abstracts

Merkel cell cancer, is a very rare, malignant, neuroendocrine tumour. of the skin The cause is not known. Is and often aggressive malignancy with high tendency for local recurrence, lymph node involvement and distant metastasis and a poor prognosis and rapid progression. The Merkel cell is located in or near the basal layer of the epidermis and is closely associated with terminal axons. The aims in this study we report four cases of Merkel cell tumor of the skin(1 primary and ...

Introduction: Cyclic Cushing’s syndrome (cCS) is a rare condition characterized by periods of excessive cortisol secretion (peaks), alternating with phases of eucortisolism (through). In most cases, cCS is caused by an ACTH-secreting pituitary tumor, while only few cases of cyclic ectopic ACTH secretion (cEAS) have been described.Case presentation: In February 2023, a 58-year-old woman was referred to our Endocrine Unit due to a 10-year history of r...