Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep625 | Pituitary and Neuroendocrinology | ECE2020

Malignant insulinoma treated with 177Lu-DOTATATE: Results in the first year post-therapy

Concepción Terroba-Larumbe María , Maria Palacio-Mures Jose , Crespo-Soto Cristina , Perez-Saborido Baltasar , Crespo-Herrero Guillermo , Ventosa-Viña Marta , Acuña-Garcia Manuel , Alejo-Ramos Mirian , Anacabe-Goyogana Itziar , Cuellar-Olmedo Luis

Introduction: Neuroendocrine tumors (NETs) are rare and their clinical behavior and prognosis correlates with mitotic rate and Ki-67 index. Most patients with advanced NET have liver metastases unresectable and somatostatin analogues are the initial therapy of choice but when disease progresses despite treatment and there are positive somatostatin receptors, peptide receptor radioligand therapy (PRRT), using lutetium-177, is a therapeutic option.Clinical...

ea0070ep372 | Pituitary and Neuroendocrinology | ECE2020

Pasireotide therapy in a patient with pituitary macroadenoma and asymptomatic acromegaly resistant to first generation somatostatin analogues

Concepción Terroba-Larumbe María , Palacio-Mures Jose Maria , Crespo-Soto Cristina , Ventosa-Viña Marta , Cuellar-Olmedo Luis , Acuña-Garcia Manuel , Anacabe-Goyogana Itziar , Areli Ticona-Spinoza Danay , Maria Delgado-Sanz Jose , Angel Rodriguez Garcia Javier

Introduction: Acromegaly increases morbidity and mortality and should be treated even in the asymptomatic phase. It is almost always caused by a GH-producing pituitary adenoma and although transsphenoidal surgery is the treatment of choice in most cases, in others, primary medical therapy is indicated.Clinical case: A 36-year-old female with a family history of thyroid functional pathology and diagnosed with micronodular goiter was evaluated in February ...

ea0073aep241 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

GLP-1 receptor agonists and bariatric surgery in nonalcoholic steatohepatitis

Soraya León , María Dolores Alcántara-Laguna , Maria José Molina , Alfonso Jesús Calañas Continente , Concepción Muñoz , Maria Angeles Galvez Moreno , Aura D. Herrera-Martínez

RationaleObesity is associated with multiple comorbidities including nonalcoholic steatohepatitis (NASH). Despite its association with increased morbidity and mortality, treatment options are limited. Some studies have suggested that glucagon-like peptide-1 receptor agonists (aGLP-1) are associated with NASH resolution. Additionally, the effects of bariatric surgery on NASH-associated liver fibrosis are controversial.Methods<p ...

ea0070aep331 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Clinical and metabolic benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i) therapy in diabetic patients with psychiatric comorbidities

Concepción Terroba-Larumbe María , Crespo-Soto Cristina , Palacio-Mures Jose Maria , Gonzalez-Sagrado Manuel , Conde-Vicente Rosa , Ventosa-Viña Marta , Peña-Lozano Silvia , Portela-Martin Ainara , Fernandez-Nuñez Marta , Calleja-Barnada Mar , Cuellar-Olmedo Luis

Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) therapyhas proven effective in type 2 diabetes but there is little data on its effect in patients with psychiatric comorbidity, who usually present worse metabolic and clinical control. The aim of this study was to evaluate if there are differences in the effect of this therapy in relation to the presence of these pathologies.Methods: 225 patients included in a therapy protocol with SGLT2i,...

ea0014p204 | (1) | ECE2007

Clinical presentation of nonclassic congenital adrenal hyperplasia &br;(NC-CAH): from suspicion to diagnosis

Román Anna Casteràs , Fernández Ma Concepción Páramo , Aguado Javier De la Fuente , Abad Elena Hervás , Rodríguez Laura Fajar , Gil Beatriz Mantiñán , Cano Reyes Luna , Iraeta Ma Antonia Rego , Rodríguez Digna , Lestón Domingo González , García-Mayor Ricardo Víctor

Background: Nonclassic congenital adrenal hyperplasia (NC-CAH) caused by mutations in CYP21B gene is an inherited disorder with various clinical forms in relation to the 21-hydroxylase (21OH) activity. Classic forms are recognized early during neonatal period as salt-wasting crisis or genital ambiguity, while non-classic form presents later with wide hyperandrogenic spectrum. Genetic testing has proved to be the definitive diagnostic method.Aim: To obser...

ea0070aep863 | Thyroid | ECE2020

Retrospective incidence of NIFTP. A large multicentre Iberic study of over 3000 neoplasms

Paja Miguel , Rosa Bella M. , Iglesias Carmela , Zafón Carles , Cameselle Jose M.l , Carnero Gemma , Póvoa Antónia , Ugalde Aitziber , Anda Emma , Fernández-Seara Pilar , Sánchez-Gómez Nancy M. , Quiceno Hernán , García-Pascual Lluis , González Clarisa , Blanco Concepción , Gómez de la Riva Inés , Capel Ismael , Mancha Isabel , Gallego Helena , Maravall Javier , Roselló Esther , Alcázar Victoria , Chao Montserrat , Lázaro Antonia , Lopez-Agulló Susana , Echeverría Saioa , Joaquín Paricio J. , Sanz Javier , Messeguer Pascual , Castaño Ángel

The newly created NIFTP category (non-invasive follicular thyroid neoplasm with papillary-like nuclear features) has had a notorious impact in the management of thyroid neoplasms. Its incidence appears to be higher in western countries than Asiatic, but there are few studies including more than one institution.Objectives: To evaluate retrospectively the incidence of NITFP in a multicentre study in two adjacent countries as well as to compare th...